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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age-dependent differences in absorption.
Streekstra EJ, Kiss M, van den Heuvel J, Nicolaï J, van den Broek P, Botden SMBI, Stommel MWJ, van Rijssel L, Ungell AL, van de Steeg E, Russel FGM, de Wildt SN. Streekstra EJ, et al. Among authors: van de steeg e. Clin Transl Sci. 2022 Oct;15(10):2392-2402. doi: 10.1111/cts.13368. Epub 2022 Aug 12. Clin Transl Sci. 2022. PMID: 35962572 Free PMC article.
Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.
Mooij MG, van de Steeg E, van Rosmalen J, Windster JD, de Koning BA, Vaes WH, van Groen BD, Tibboel D, Wortelboer HM, de Wildt SN. Mooij MG, et al. Among authors: van rosmalen j, van groen bd, van de steeg e, de koning ba, de wildt sn. Drug Metab Dispos. 2016 Jul;44(7):1005-13. doi: 10.1124/dmd.115.068577. Epub 2016 Apr 21. Drug Metab Dispos. 2016. PMID: 27103634
Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs.
Notenboom S, Weigand KM, Proost JH, van Lipzig MMH, van de Steeg E, van den Broek PHH, Greupink R, Russel FGM, Groothuis GMM. Notenboom S, et al. Among authors: van den broek phh, van lipzig mmh, van de steeg e. Eur J Pharm Sci. 2018 Mar 30;115:175-184. doi: 10.1016/j.ejps.2018.01.007. Epub 2018 Jan 5. Eur J Pharm Sci. 2018. PMID: 29309877 Free article.
Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184].
Notenboom S, Weigand KM, Proost JH, van Lipzig MM, van de Steeg E, van den Broek PHH, Greupink R, Russel FGM, Groothuis GMM. Notenboom S, et al. Among authors: van den broek phh, van de steeg e, van lipzig mm. Eur J Pharm Sci. 2018 May 30;117:392-393. doi: 10.1016/j.ejps.2018.04.005. Eur J Pharm Sci. 2018. PMID: 29650218 No abstract available.
Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants.
van Groen BD, van de Steeg E, Mooij MG, van Lipzig MMH, de Koning BAE, Verdijk RM, Wortelboer HM, Gaedigk R, Bi C, Leeder JS, van Schaik RHN, van Rosmalen J, Tibboel D, Vaes WH, de Wildt SN. van Groen BD, et al. Among authors: van rosmalen j, de koning bae, van de steeg e, van lipzig mmh, van schaik rhn, de wildt sn. Eur J Pharm Sci. 2018 Nov 1;124:217-227. doi: 10.1016/j.ejps.2018.08.042. Epub 2018 Aug 30. Eur J Pharm Sci. 2018. PMID: 30171984 Free article.
Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.
Bosgra S, van de Steeg E, Vlaming ML, Verhoeckx KC, Huisman MT, Verwei M, Wortelboer HM. Bosgra S, et al. Among authors: van de steeg e. Eur J Pharm Sci. 2014 Dec 18;65:156-66. doi: 10.1016/j.ejps.2014.09.007. Epub 2014 Sep 28. Eur J Pharm Sci. 2014. PMID: 25261337
47 results