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Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Medina-Gomez C, Kemp JP, Trajanoska K, Luan J, Chesi A, Ahluwalia TS, Mook-Kanamori DO, Ham A, Hartwig FP, Evans DS, Joro R, Nedeljkovic I, Zheng HF, Zhu K, Atalay M, Liu CT, Nethander M, Broer L, Porleifsson G, Mullin BH, Handelman SK, Nalls MA, Jessen LE, Heppe DHM, Richards JB, Wang C, Chawes B, Schraut KE, Amin N, Wareham N, Karasik D, Van der Velde N, Ikram MA, Zemel BS, Zhou Y, Carlsson CJ, Liu Y, McGuigan FE, Boer CG, Bønnelykke K, Ralston SH, Robbins JA, Walsh JP, Zillikens MC, Langenberg C, Li-Gao R, Williams FMK, Harris TB, Akesson K, Jackson RD, Sigurdsson G, den Heijer M, van der Eerden BCJ, van de Peppel J, Spector TD, Pennell C, Horta BL, Felix JF, Zhao JH, Wilson SG, de Mutsert R, Bisgaard H, Styrkársdóttir U, Jaddoe VW, Orwoll E, Lakka TA, Scott R, Grant SFA, Lorentzon M, van Duijn CM, Wilson JF, Stefansson K, Psaty BM, Kiel DP, Ohlsson C, Ntzani E, van Wijnen AJ, Forgetta V, Ghanbari M, Logan JG, Williams GR, Bassett JHD, Croucher PI, Evangelou E, Uitterlinden AG, Ackert-Bicknell CL, Tobias JH, Evans DM, Rivadeneira F. Medina-Gomez C, et al. Among authors: van duijn cm, van der eerden bcj, van wijnen aj, van de peppel j, van der velde n, de mutsert r. Am J Hum Genet. 2018 Jan 4;102(1):88-102. doi: 10.1016/j.ajhg.2017.12.005. Am J Hum Genet. 2018. PMID: 29304378 Free PMC article.
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Kemp JP, Medina-Gomez C, Estrada K, St Pourcain B, Heppe DH, Warrington NM, Oei L, Ring SM, Kruithof CJ, Timpson NJ, Wolber LE, Reppe S, Gautvik K, Grundberg E, Ge B, van der Eerden B, van de Peppel J, Hibbs MA, Ackert-Bicknell CL, Choi K, Koller DL, Econs MJ, Williams FM, Foroud T, Zillikens MC, Ohlsson C, Hofman A, Uitterlinden AG, Davey Smith G, Jaddoe VW, Tobias JH, Rivadeneira F, Evans DM. Kemp JP, et al. Among authors: van de peppel j, van der eerden b. PLoS Genet. 2014 Jun 19;10(6):e1004423. doi: 10.1371/journal.pgen.1004423. eCollection 2014 Jun. PLoS Genet. 2014. PMID: 24945404 Free PMC article.
Identification of microRNAs in human plasma.
van der Eerden BC, Alves RD, Kockx CE, Ozgur Z, Schreuders-Koedam M, van de Peppel J, van Ijcken WF, van Leeuwen JP. van der Eerden BC, et al. Among authors: van de peppel j, van leeuwen jp, van ijcken wf. Methods Mol Biol. 2015;1226:71-85. doi: 10.1007/978-1-4939-1619-1_7. Methods Mol Biol. 2015. PMID: 25331044
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway.
Brum AM, van de Peppel J, van der Leije CS, Schreuders-Koedam M, Eijken M, van der Eerden BC, van Leeuwen JP. Brum AM, et al. Among authors: van der leije cs, van de peppel j, van leeuwen jp, van der eerden bc. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12711-6. doi: 10.1073/pnas.1501597112. Epub 2015 Sep 29. Proc Natl Acad Sci U S A. 2015. PMID: 26420877 Free PMC article.
Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells.
Morhayim J, van de Peppel J, Braakman E, Rombouts EW, Ter Borg MN, Dudakovic A, Chiba H, van der Eerden BC, Raaijmakers MH, van Wijnen AJ, Cornelissen JJ, van Leeuwen JP. Morhayim J, et al. Among authors: van wijnen aj, van de peppel j, van leeuwen jp, van der eerden bc. Sci Rep. 2016 Sep 2;6:32034. doi: 10.1038/srep32034. Sci Rep. 2016. PMID: 27585950 Free PMC article.
Comparative proteomic profiling of human osteoblast-derived extracellular matrices identifies proteins involved in mesenchymal stromal cell osteogenic differentiation and mineralization.
Baroncelli M, van der Eerden BC, Kan YY, Alves RD, Demmers JA, van de Peppel J, van Leeuwen JP. Baroncelli M, et al. Among authors: van de peppel j, van leeuwen jp, van der eerden bc. J Cell Physiol. 2018 Jan;233(1):387-395. doi: 10.1002/jcp.25898. Epub 2017 May 19. J Cell Physiol. 2018. PMID: 28272740
Molecular characterization of human osteoblast-derived extracellular vesicle mRNA using next-generation sequencing.
Morhayim J, van de Peppel J, Dudakovic A, Chiba H, van Wijnen AJ, van Leeuwen JP. Morhayim J, et al. Among authors: van wijnen aj, van de peppel j, van leeuwen jp. Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1133-1141. doi: 10.1016/j.bbamcr.2017.03.011. Epub 2017 Mar 24. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28347747 Free PMC article.
52 results