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Fibroblast Growth Factor Signaling in Metabolic Regulation.
Nies VJ, Sancar G, Liu W, van Zutphen T, Struik D, Yu RT, Atkins AR, Evans RM, Jonker JW, Downes MR. Nies VJ, et al. Among authors: van zutphen t. Front Endocrinol (Lausanne). 2016 Jan 19;6:193. doi: 10.3389/fendo.2015.00193. eCollection 2015. Front Endocrinol (Lausanne). 2016. PMID: 26834701 Free PMC article. Review.
Role of bile acid receptor FXR in development and function of brown adipose tissue.
Yang J, de Vries HD, Mayeuf-Louchart A, Stroeve JH, Bloks VW, Koehorst M, Duez H, Staels B, Kuipers F, van Zutphen T. Yang J, et al. Among authors: van zutphen t. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Feb;1868(2):159257. doi: 10.1016/j.bbalip.2022.159257. Epub 2022 Nov 17. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 36402299 Free article.
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease.
Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW. Liu W, et al. Among authors: van zutphen t. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2288-93. doi: 10.1073/pnas.1525093113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858440 Free PMC article.
Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction.
van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, de Moraes RA, Zhang L, Wolters JC, Bischoff R, Wanders RJ, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH. van Zutphen T, et al. J Hepatol. 2016 Dec;65(6):1198-1208. doi: 10.1016/j.jhep.2016.05.046. Epub 2016 Jun 14. J Hepatol. 2016. PMID: 27312946 Free article.
FGF1 and insulin control lipolysis by convergent pathways.
Sancar G, Liu S, Gasser E, Alvarez JG, Moutos C, Kim K, van Zutphen T, Wang Y, Huddy TF, Ross B, Dai Y, Zepeda D, Collins B, Tilley E, Kolar MJ, Yu RT, Atkins AR, van Dijk TH, Saghatelian A, Jonker JW, Downes M, Evans RM. Sancar G, et al. Among authors: van zutphen t, van dijk th. Cell Metab. 2022 Jan 4;34(1):171-183.e6. doi: 10.1016/j.cmet.2021.12.004. Cell Metab. 2022. PMID: 34986332 Free PMC article.
Autocrine FGF1 signaling promotes glucose uptake in adipocytes.
Nies VJM, Struik D, Liu S, Liu W, Kruit JK, Downes M, van Zutphen T, Verkade HJ, Evans RM, Jonker JW. Nies VJM, et al. Among authors: van zutphen t. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2122382119. doi: 10.1073/pnas.2122382119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161959 Free PMC article.
Identification of an alternative triglyceride biosynthesis pathway.
McLelland GL, Lopez-Osias M, Verzijl CRC, Ellenbroek BD, Oliveira RA, Boon NJ, Dekker M, van den Hengel LG, Ali R, Janssen H, Song JY, Krimpenfort P, van Zutphen T, Jonker JW, Brummelkamp TR. McLelland GL, et al. Among authors: van zutphen t. Nature. 2023 Sep;621(7977):171-178. doi: 10.1038/s41586-023-06497-4. Epub 2023 Aug 30. Nature. 2023. PMID: 37648867 Free PMC article.
42 results