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Asp179 in the class A β-lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis.
FEBS J. 2023 Oct;290(20):4933-4949. doi: 10.1111/febs.16892. Epub 2023 Jul 2.
FEBS J. 2023.
PMID: 37335937
Two β-Lactamase Variants with Reduced Clavulanic Acid Inhibition Display Different Millisecond Dynamics.
Elings W, Chikunova A, van Zanten DB, Drenth R, Ahmad MUD, Blok AJ, Timmer M, Perrakis A, Ubbink M.
Elings W, et al. Among authors: van zanten db.
Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0262820. doi: 10.1128/AAC.02628-20. Epub 2021 Jul 16.
Antimicrob Agents Chemother. 2021.
PMID: 34031049
Free PMC article.
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