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Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH.
FASEB J. 2022 Aug;36(8):e22435. doi: 10.1096/fj.202200111R.
FASEB J. 2022.
PMID: 35830259
Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice.
Seidel F, Kleemann R, van Duyvenvoorde W, van Trigt N, Keijzer N, van der Kooij S, van Kooten C, Verschuren L, Menke A, Kiliaan AJ, Winter J, Hughes TR, Morgan BP, Baas F, Fluiter K, Morrison MC.
Seidel F, et al. Among authors: van trigt n.
Int J Mol Sci. 2022 Sep 14;23(18):10736. doi: 10.3390/ijms231810736.
Int J Mol Sci. 2022.
PMID: 36142647
Free PMC article.
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A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Kroon J, Schilperoort M, In Het Panhuis W, van den Berg R, van Doeselaar L, Verzijl CRC, van Trigt N, Mol IM, Sips HHCM, van den Heuvel JK, Koorneef LL, van der Sluis RJ, Fenzl A, Kiefer FW, Vettorazzi S, Tuckermann JP, Biermasz NR, Meijer OC, Rensen PCN, Kooijman S.
Kroon J, et al. Among authors: van trigt n.
Mol Metab. 2021 May;47:101179. doi: 10.1016/j.molmet.2021.101179. Epub 2021 Feb 3.
Mol Metab. 2021.
PMID: 33548499
Free PMC article.
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