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A Comprehensive Analysis of the Erythropoietin-erythroferrone-hepcidin Pathway in Hereditary Hemolytic Anemias.
van Vuren AJ, Sharfo A, Grootendorst ST, van Straaten S, Punt AM, Petersen JB, El Fassi D, van Solinge WW, Bartels M, van Wijk R, Glenthøj A, van Beers EJ. van Vuren AJ, et al. Among authors: van straaten s. Hemasphere. 2021 Aug 11;5(9):e627. doi: 10.1097/HS9.0000000000000627. eCollection 2021 Sep. Hemasphere. 2021. PMID: 34396049 Free PMC article. No abstract available.
A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease From Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling.
van Vuren AJ, van Straaten S, Mokry M, van Wijk R, van Beers EJ. van Vuren AJ, et al. Among authors: van straaten s. Hemasphere. 2021 Feb 10;5(3):e531. doi: 10.1097/HS9.0000000000000531. eCollection 2021 Mar. Hemasphere. 2021. PMID: 33604514 Free PMC article. No abstract available.
Organ involvement occurs in all forms of hereditary haemolytic anaemia.
van Straaten S, Verhoeven J, Hagens S, Schutgens R, van Solinge W, van Wijk R, van Beers EJ. van Straaten S, et al. Br J Haematol. 2019 May;185(3):602-605. doi: 10.1111/bjh.15575. Epub 2018 Sep 5. Br J Haematol. 2019. PMID: 30183081 Free article. Clinical Trial. No abstract available.
AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes.
Rab MAE, Van Oirschot BA, Kosinski PA, Hixon J, Johnson K, Chubukov V, Dang L, Pasterkamp G, Van Straaten S, Van Solinge WW, Van Beers EJ, Kung C, Van Wijk R. Rab MAE, et al. Among authors: van straaten s. Haematologica. 2021 Jan 1;106(1):238-249. doi: 10.3324/haematol.2019.238865. Haematologica. 2021. PMID: 31974203 Free PMC article.
Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy.
Rab MAE, Bos J, van Oirschot BA, van Straaten S, Kosinski PA, Chubukov V, Kim H, Mangus H, Schutgens REG, Pasterkamp G, Dang L, Kung C, van Beers EJ, van Wijk R. Rab MAE, et al. Among authors: van straaten s. Blood. 2021 May 27;137(21):2997-3001. doi: 10.1182/blood.2020008635. Blood. 2021. PMID: 33690814 Free PMC article. No abstract available.
Worldwide study of hematopoietic allogeneic stem cell transplantation in pyruvate kinase deficiency.
van Straaten S, Bierings M, Bianchi P, Akiyoshi K, Kanno H, Serra IB, Chen J, Huang X, van Beers E, Ekwattanakit S, Güngör T, Kors WA, Smiers F, Raymakers R, Yanez L, Sevilla J, van Solinge W, Segovia JC, van Wijk R. van Straaten S, et al. Haematologica. 2018 Feb;103(2):e82-e86. doi: 10.3324/haematol.2017.177857. Epub 2017 Dec 14. Haematologica. 2018. PMID: 29242305 Free PMC article. No abstract available.
Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study.
van Beers EJ, van Straaten S, Morton DH, Barcellini W, Eber SW, Glader B, Yaish HM, Chonat S, Kwiatkowski JL, Rothman JA, Sharma M, Neufeld EJ, Sheth S, Despotovic JM, Kollmar N, Pospíšilová D, Knoll CM, Kuo K, Pastore YD, Thompson AA, Newburger PE, Ravindranath Y, Wang WC, Wlodarski MW, Wang H, Holzhauer S, Breakey VR, Verhovsek M, Kunz J, McNaull MA, Rose MJ, Bradeen HA, Addonizio K, Li A, Al-Sayegh H, London WB, Grace RF. van Beers EJ, et al. Among authors: van straaten s. Haematologica. 2019 Feb;104(2):e51-e53. doi: 10.3324/haematol.2018.196295. Epub 2018 Sep 13. Haematologica. 2019. PMID: 30213831 Free PMC article. No abstract available.
Distinctive roles of neutrophils and monocytes in anti-thy-1 nephritis.
Westerhuis R, van Straaten SC, van Dixhoorn MG, van Rooijen N, Verhagen NA, Dijkstra CD, de Heer E, Daha MR. Westerhuis R, et al. Among authors: van rooijen n, van straaten sc, van dixhoorn mg. Am J Pathol. 2000 Jan;156(1):303-10. doi: 10.1016/S0002-9440(10)64731-1. Am J Pathol. 2000. PMID: 10623679 Free PMC article.
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