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Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, van Rooijen N, García-Sastre A, Stanley ER, Ginhoux F, Frenette PS, Merad M. Hashimoto D, et al. Among authors: van rooijen n. Immunity. 2013 Apr 18;38(4):792-804. doi: 10.1016/j.immuni.2013.04.004. Immunity. 2013. PMID: 23601688 Free PMC article.
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation.
Hashimoto D, Chow A, Greter M, Saenger Y, Kwan WH, Leboeuf M, Ginhoux F, Ochando JC, Kunisaki Y, van Rooijen N, Liu C, Teshima T, Heeger PS, Stanley ER, Frenette PS, Merad M. Hashimoto D, et al. Among authors: van rooijen n. J Exp Med. 2011 May 9;208(5):1069-82. doi: 10.1084/jem.20101709. Epub 2011 May 2. J Exp Med. 2011. PMID: 21536742 Free PMC article.
Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity.
Gautier EL, Chow A, Spanbroek R, Marcelin G, Greter M, Jakubzick C, Bogunovic M, Leboeuf M, van Rooijen N, Habenicht AJ, Merad M, Randolph GJ. Gautier EL, et al. Among authors: van rooijen n. J Immunol. 2012 Sep 1;189(5):2614-24. doi: 10.4049/jimmunol.1200495. Epub 2012 Aug 1. J Immunol. 2012. PMID: 22855714 Free PMC article.
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes.
Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ. Jakubzick C, et al. Among authors: van rooijen n. Immunity. 2013 Sep 19;39(3):599-610. doi: 10.1016/j.immuni.2013.08.007. Epub 2013 Sep 5. Immunity. 2013. PMID: 24012416 Free PMC article.
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.
Chow A, Lucas D, Hidalgo A, Méndez-Ferrer S, Hashimoto D, Scheiermann C, Battista M, Leboeuf M, Prophete C, van Rooijen N, Tanaka M, Merad M, Frenette PS. Chow A, et al. Among authors: van rooijen n. J Exp Med. 2011 Feb 14;208(2):261-71. doi: 10.1084/jem.20101688. Epub 2011 Jan 31. J Exp Med. 2011. PMID: 21282381 Free PMC article.
The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12.
Hernandez L, Smirnova T, Kedrin D, Wyckoff J, Zhu L, Stanley ER, Cox D, Muller WJ, Pollard JW, Van Rooijen N, Segall JE. Hernandez L, et al. Among authors: van rooijen n. Cancer Res. 2009 Apr 1;69(7):3221-7. doi: 10.1158/0008-5472.CAN-08-2871. Epub 2009 Mar 17. Cancer Res. 2009. PMID: 19293185 Free PMC article.
861 results