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Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies.
Lewis RW, Andrus AK, Arroyo J, Brescia S, Botham PA, Corvaro M, Daston GP, Hofmann T, Rodriguez C, Sewell F, van Ravenzwaay B, Wiench K, Marty S. Lewis RW, et al. Among authors: van ravenzwaay b. Regul Toxicol Pharmacol. 2024 Mar;148:105585. doi: 10.1016/j.yrtph.2024.105585. Epub 2024 Feb 24. Regul Toxicol Pharmacol. 2024. PMID: 38403008 Free article. Review.
Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice.
Viant MR, Amstalden E, Athersuch T, Bouhifd M, Camuzeaux S, Crizer DM, Driemert P, Ebbels T, Ekman D, Flick B, Giri V, Gómez-Romero M, Haake V, Herold M, Kende A, Lai F, Leonards PEG, Lim PP, Lloyd GR, Mosley J, Namini C, Rice JR, Romano S, Sands C, Smith MJ, Sobanski T, Southam AD, Swindale L, van Ravenzwaay B, Walk T, Weber RJM, Zickgraf FM, Kamp H. Viant MR, et al. Among authors: van ravenzwaay b. Arch Toxicol. 2024 Apr;98(4):1111-1123. doi: 10.1007/s00204-024-03680-y. Epub 2024 Feb 18. Arch Toxicol. 2024. PMID: 38368582 Free PMC article.
Utility of in vivo metabolomics to support read-across for UVCB substances under REACH.
Kamp H, Kocabas NA, Faulhammer F, Synhaeve N, Rushton E, Flick B, Giri V, Sperber S, Higgins LG, Penman MG, van Ravenzwaay B, Rooseboom M. Kamp H, et al. Among authors: van ravenzwaay b. Arch Toxicol. 2024 Mar;98(3):755-768. doi: 10.1007/s00204-023-03638-6. Epub 2024 Jan 24. Arch Toxicol. 2024. PMID: 38265474 Free PMC article.
The short-term toxicity and metabolome of dicyclopentadiene.
van Ravenzwaay B, Kocabas NA, Faulhammer F, Flick B, Giri V, Sperber S, Penman MG, Higgins LG, Kamp H, Rooseboom M. van Ravenzwaay B, et al. Toxicol Lett. 2024 Mar;393:57-68. doi: 10.1016/j.toxlet.2024.01.005. Epub 2024 Jan 12. Toxicol Lett. 2024. PMID: 38219808 Free article.
Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoin.
Ramirez-Hincapie S, Birk B, Ternes P, Giri V, Zickgraf FM, Haake V, Herold M, Kamp H, Driemert P, Landsiedel R, Richling E, Funk-Weyer D, van Ravenzwaay B. Ramirez-Hincapie S, et al. Among authors: van ravenzwaay b. Arch Toxicol. 2023 Nov;97(11):2903-2917. doi: 10.1007/s00204-023-03572-7. Epub 2023 Sep 4. Arch Toxicol. 2023. PMID: 37665362 Free PMC article.
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS).
Melching-Kollmuss S, Bothe K, Charlton A, Gangadharan B, Ghaffari R, Jacobi S, Marty S, Marxfeld HA, McInnes EF, Sauer UG, Sheets LP, Strupp C, Tinwell H, Wiemann C, Botham PA, van Ravenzwaay B. Melching-Kollmuss S, et al. Among authors: van ravenzwaay b. Crit Rev Toxicol. 2023 Jul;53(6):339-371. doi: 10.1080/10408444.2023.2231033. Epub 2023 Aug 9. Crit Rev Toxicol. 2023. PMID: 37554099 Review.
New approach methodologies in human regulatory toxicology - Not if, but how and when!
Schmeisser S, Miccoli A, von Bergen M, Berggren E, Braeuning A, Busch W, Desaintes C, Gourmelon A, Grafström R, Harrill J, Hartung T, Herzler M, Kass GEN, Kleinstreuer N, Leist M, Luijten M, Marx-Stoelting P, Poetz O, van Ravenzwaay B, Roggeband R, Rogiers V, Roth A, Sanders P, Thomas RS, Marie Vinggaard A, Vinken M, van de Water B, Luch A, Tralau T. Schmeisser S, et al. Among authors: van ravenzwaay b. Environ Int. 2023 Aug;178:108082. doi: 10.1016/j.envint.2023.108082. Epub 2023 Jul 4. Environ Int. 2023. PMID: 37422975 Free article. Review.
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity.
Gant TW, Auerbach SS, Von Bergen M, Bouhifd M, Botham PA, Caiment F, Currie RA, Harrill J, Johnson K, Li D, Rouquie D, van Ravenzwaay B, Sistare F, Tralau T, Viant MR, van de Laan JW, Yauk C. Gant TW, et al. Among authors: van ravenzwaay b. Arch Toxicol. 2023 Aug;97(8):2291-2302. doi: 10.1007/s00204-023-03522-3. Epub 2023 Jun 9. Arch Toxicol. 2023. PMID: 37296313 Free PMC article.
219 results