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Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
Wellaway CR, Baldwin IR, Bamborough P, Barker D, Bartholomew MA, Chung CW, Dümpelfeld B, Evans JP, Fazakerley NJ, Homes P, Keeling SP, Lewell XQ, McNab FW, Morley J, Needham D, Neu M, van Oosterhout AJM, Pal A, Reinhard FBM, Rianjongdee F, Robertson CM, Rowland P, Shah RR, Sherriff EB, Sloan LA, Teague S, Thomas DA, Wellaway N, Wojno-Picon J, Woolven JM, Coe DM. Wellaway CR, et al. Among authors: van oosterhout ajm. J Med Chem. 2022 Jan 13;65(1):633-664. doi: 10.1021/acs.jmedchem.1c01765. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928601
Pulmonary Innate Lymphoid Cell Responses during Rhinovirus-induced Asthma Exacerbations In Vivo: A Clinical Trial.
Dhariwal J, Cameron A, Wong E, Paulsen M, Trujillo-Torralbo MB, Del Rosario A, Bakhsoliani E, Kebadze T, Almond M, Farne H, Gogsadze L, Aniscenko J, Rana BMJ, Hansel TT, Jackson DJ, Kon OM, Edwards MR, Solari R, Cousins DJ, Walton RP, Johnston SL; MRC-GSK Strategic Alliance Consortium. Dhariwal J, et al. Am J Respir Crit Care Med. 2021 Dec 1;204(11):1259-1273. doi: 10.1164/rccm.202010-3754OC. Am J Respir Crit Care Med. 2021. PMID: 34469272 Free PMC article. Clinical Trial.
Identification of asthma-associated microRNAs in bronchial biopsies.
Roffel MP, Boudewijn IM, van Nijnatten JLL, Faiz A, Vermeulen CJ, van Oosterhout AJ, Affleck K, Timens W, Bracke KR, Maes T, Heijink IH, Brandsma CA, van den Berge M. Roffel MP, et al. Among authors: van oosterhout aj. Eur Respir J. 2022 Mar 17;59(3):2101294. doi: 10.1183/13993003.01294-2021. Print 2022 Mar. Eur Respir J. 2022. PMID: 34446467 Free article.
Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium.
McErlean P, Kelly A, Dhariwal J, Kirtland M, Watson J, Ranz I, Smith J, Saxena A, Cousins DJ, Van Oosterhout A, Solari R, Edwards MR, Johnston SL, Lavender P. McErlean P, et al. Among authors: van oosterhout a. Front Genet. 2020 Dec 10;11:585746. doi: 10.3389/fgene.2020.585746. eCollection 2020. Front Genet. 2020. PMID: 33362848 Free PMC article.
Respiratory Syncytial Virus Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells.
Simpson J, Loh Z, Ullah MA, Lynch JP, Werder RB, Collinson N, Zhang V, Dondelinger Y, Bertrand MJM, Everard ML, Blyth CC, Hartel G, Van Oosterhout AJ, Gough PJ, Bertin J, Upham JW, Spann KM, Phipps S. Simpson J, et al. Among authors: van oosterhout aj. Am J Respir Crit Care Med. 2020 Jun 1;201(11):1358-1371. doi: 10.1164/rccm.201906-1149OC. Am J Respir Crit Care Med. 2020. PMID: 32105156
188 results