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Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia.
Haroun-Izquierdo A, Vincenti M, Netskar H, van Ooijen H, Zhang B, Bendzick L, Kanaya M, Momayyezi P, Li S, Wiiger MT, Hoel HJ, Krokeide SZ, Kremer V, Tjonnfjord G, Berggren S, Wikström K, Blomberg P, Alici E, Felices M, Önfelt B, Höglund P, Valamehr B, Ljunggren HG, Björklund A, Hammer Q, Kveberg L, Cichocki F, Miller JS, Malmberg KJ, Sohlberg E. Haroun-Izquierdo A, et al. Among authors: van ooijen h. J Immunother Cancer. 2022 Nov;10(11):e005577. doi: 10.1136/jitc-2022-005577. J Immunother Cancer. 2022. PMID: 36319065 Free PMC article.
Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip.
Sandström N, Carannante V, Olofsson K, Sandoz PA, Moussaud-Lamodière EL, Seashore-Ludlow B, Van Ooijen H, Verron Q, Frisk T, Takai M, Wiklund M, Östling P, Önfelt B. Sandström N, et al. Among authors: van ooijen h. Cell Rep Methods. 2022 Jul 18;2(7):100256. doi: 10.1016/j.crmeth.2022.100256. eCollection 2022 Jul 18. Cell Rep Methods. 2022. PMID: 35880015 Free PMC article.
Molecular pixelation: spatial proteomics of single cells by sequencing.
Karlsson F, Kallas T, Thiagarajan D, Karlsson M, Schweitzer M, Navarro JF, Leijonancker L, Geny S, Pettersson E, Rhomberg-Kauert J, Larsson L, van Ooijen H, Petkov S, González-Granillo M, Bunz J, Dahlberg J, Simonetti M, Sathe P, Brodin P, Barrio AM, Fredriksson S. Karlsson F, et al. Among authors: van ooijen h. Nat Methods. 2024 May 8. doi: 10.1038/s41592-024-02268-9. Online ahead of print. Nat Methods. 2024. PMID: 38720062
Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells.
Hammer Q, Perica K, van Ooijen H, Mbofung R, Momayyezi P, Varady E, Martin KE, Pan Y, Jelcic M, Groff B, Abujarour R, Krokeide S, Lee T, Williams A, Goodridge JP, Valamehr B, Önfelt B, Sadelain M, Malmberg KJ. Hammer Q, et al. Among authors: van ooijen h. bioRxiv [Preprint]. 2023 Oct 9:2023.10.09.557143. doi: 10.1101/2023.10.09.557143. bioRxiv. 2023. PMID: 37873468 Free PMC article. Preprint.
FOXO transcriptional activity is associated with response to chemoradiation in EAC.
Creemers A, van der Zalm AP, van de Stolpe A, Holtzer L, Stoffels M, Hooijer GKJ, Ebbing EA, van Ooijen H, van Brussel AGC, Aussems-Custers EMG, van Berge Henegouwen MI, Hulshof MCCM, Bergman JJGHM, Meijer SL, Bijlsma MF, van Laarhoven HWM. Creemers A, et al. Among authors: van ooijen h. J Transl Med. 2022 Apr 25;20(1):183. doi: 10.1186/s12967-022-03376-w. J Transl Med. 2022. PMID: 35468793 Free PMC article.
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