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Inhibition of TLR4 signalling to dampen joint inflammation in osteoarthritis.
Bartels YL, van Lent PLEM, van der Kraan PM, Blom AB, Bonger KM, van den Bosch MHJ. Bartels YL, et al. Among authors: van lent plem. Rheumatology (Oxford). 2024 Mar 1;63(3):608-618. doi: 10.1093/rheumatology/kead493. Rheumatology (Oxford). 2024. PMID: 37788083 Free PMC article. Review.
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Blom AB, Radstake TR, Holthuysen AE, Slöetjes AW, Pesman GJ, Sweep FG, van de Loo FA, Joosten LA, Barrera P, van Lent PL, van den Berg WB. Blom AB, et al. Arthritis Rheum. 2003 Apr;48(4):1002-14. doi: 10.1002/art.10871. Arthritis Rheum. 2003. PMID: 12687542 Free article.
The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.
van Lent P, Nabbe KC, Boross P, Blom AB, Roth J, Holthuysen A, Sloetjes A, Verbeek S, van den Berg W. van Lent P, et al. Am J Pathol. 2003 Nov;163(5):1839-48. doi: 10.1016/s0002-9440(10)63543-2. Am J Pathol. 2003. PMID: 14578184 Free PMC article.
NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis.
van Lent PL, Nabbe KC, Blom AB, Sloetjes A, Holthuysen AE, Kolls J, Van De Loo FA, Holland SM, Van Den Berg WB. van Lent PL, et al. Arthritis Res Ther. 2005;7(4):R885-95. doi: 10.1186/ar1760. Epub 2005 May 20. Arthritis Res Ther. 2005. PMID: 15987491 Free PMC article.
109 results