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PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance.
van Gulijk M, van Krimpen A, Schetters S, Eterman M, van Elsas M, Mankor J, Klaase L, de Bruijn M, van Nimwegen M, van Tienhoven T, van Ijcken W, Boon L, van der Schoot J, Verdoes M, Scheeren F, van der Burg SH, Lambrecht BN, Stadhouders R, Dammeijer F, Aerts J, van Hall T. van Gulijk M, et al. Among authors: van krimpen a. Sci Immunol. 2023 May 19;8(83):eabn6173. doi: 10.1126/sciimmunol.abn6173. Epub 2023 May 19. Sci Immunol. 2023. PMID: 37205768
Immunomodulatory Effects of Stereotactic Body Radiotherapy and Vaccination with Heat-Killed Mycobacterium Obuense (IMM-101) in Patients with Locally Advanced Pancreatic Cancer.
van 't Land FR, Lau SP, de Koning W, Klaase L, Vink M, van Krimpen A, Dumas J, Vadgama D, Nuyttens JJ, Mustafa DAM, Stadhouders R, Willemsen M, Stubbs AP, Aerts JG, van Eijck CHJ. van 't Land FR, et al. Among authors: van krimpen a. Cancers (Basel). 2022 Oct 27;14(21):5299. doi: 10.3390/cancers14215299. Cancers (Basel). 2022. PMID: 36358718 Free PMC article.
Immune suppression in the tumor-draining lymph node corresponds with distant disease recurrence in patients with melanoma.
van Krimpen A, Gerretsen VIV, Mulder EEAP, van Gulijk M, van den Bosch TPP, von der Thüsen J, Grünhagen DJ, Verhoef C, Mustafa D, Aerts JG, Stadhouders R, Dammeijer F. van Krimpen A, et al. Cancer Cell. 2022 Aug 8;40(8):798-799. doi: 10.1016/j.ccell.2022.06.009. Epub 2022 Jul 14. Cancer Cell. 2022. PMID: 35839777 Free article. No abstract available.
Autologous dendritic cells pulsed with allogeneic tumour cell lysate induce tumour-reactive T-cell responses in patients with pancreatic cancer: A phase I study.
Lau SP, Klaase L, Vink M, Dumas J, Bezemer K, van Krimpen A, van der Breggen R, Wismans LV, Doukas M, de Koning W, Stubbs AP, Mustafa DAM, Vroman H, Stadhouders R, Nunes JB, Stingl C, de Miranda NFCC, Luider TM, van der Burg SH, Aerts JG, van Eijck CHJ. Lau SP, et al. Among authors: van krimpen a. Eur J Cancer. 2022 Jul;169:20-31. doi: 10.1016/j.ejca.2022.03.015. Epub 2022 Apr 28. Eur J Cancer. 2022. PMID: 35490565 Free article. Clinical Trial.