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The Influence of Human IgG Subclass and Allotype on Complement Activation.
Damelang T, de Taeye SW, Rentenaar R, Roya-Kouchaki K, de Boer E, Derksen NIL, van Kessel K, Lissenberg-Thunnissen S, Rooijakkers SHM, Jongerius I, Mebius MM, Schuurman J, Labrijn AF, Vidarsson G, Rispens T. Damelang T, et al. Among authors: van kessel k. J Immunol. 2023 Dec 1;211(11):1725-1735. doi: 10.4049/jimmunol.2300307. J Immunol. 2023. PMID: 37843500 Free PMC article.
Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis.
Cruz AR, Bentlage AEH, Blonk R, de Haas CJC, Aerts PC, Scheepmaker LM, Bouwmeester IG, Lux A, van Strijp JAG, Nimmerjahn F, van Kessel KPM, Vidarsson G, Rooijakkers SHM. Cruz AR, et al. Among authors: van kessel kpm. J Immunol. 2022 Sep 15;209(6):1146-1155. doi: 10.4049/jimmunol.2200080. Epub 2022 Aug 24. J Immunol. 2022. PMID: 36002230
Staphylococcus aureus formyl peptide receptor-like 1 inhibitor (FLIPr) and its homologue FLIPr-like are potent FcγR antagonists that inhibit IgG-mediated effector functions.
Stemerding AM, Köhl J, Pandey MK, Kuipers A, Leusen JH, Boross P, Nederend M, Vidarsson G, Weersink AY, van de Winkel JG, van Kessel KP, van Strijp JA. Stemerding AM, et al. Among authors: van kessel kp, van strijp ja, van de winkel jg. J Immunol. 2013 Jul 1;191(1):353-62. doi: 10.4049/jimmunol.1203243. Epub 2013 Jun 5. J Immunol. 2013. PMID: 23740955
Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma.
de Vor L, Beudeker CR, Flier A, Scheepmaker LM, Aerts PC, Vijlbrief DC, Bekker MN, Beurskens FJ, van Kessel KPM, de Haas CJC, Rooijakkers SHM, van der Flier M. de Vor L, et al. Front Immunol. 2022 Jul 29;13:933251. doi: 10.3389/fimmu.2022.933251. eCollection 2022. Front Immunol. 2022. PMID: 35967335 Free PMC article.
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation.
Cruz AR, Boer MAD, Strasser J, Zwarthoff SA, Beurskens FJ, de Haas CJC, Aerts PC, Wang G, de Jong RN, Bagnoli F, van Strijp JAG, van Kessel KPM, Schuurman J, Preiner J, Heck AJR, Rooijakkers SHM. Cruz AR, et al. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e2016772118. doi: 10.1073/pnas.2016772118. Proc Natl Acad Sci U S A. 2021. PMID: 33563762 Free PMC article.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
Zwarthoff SA, Widmer K, Kuipers A, Strasser J, Ruyken M, Aerts PC, de Haas CJC, Ugurlar D, den Boer MA, Vidarsson G, van Strijp JAG, Gros P, Parren PWHI, van Kessel KPM, Preiner J, Beurskens FJ, Schuurman J, Ricklin D, Rooijakkers SHM. Zwarthoff SA, et al. Among authors: van strijp jag, van kessel kpm. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2102787118. doi: 10.1073/pnas.2102787118. Proc Natl Acad Sci U S A. 2021. PMID: 34155115 Free PMC article.
220 results