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Trinucleotide-repeat expanded and normal DMPK transcripts contain unusually long poly(A) tails despite differential nuclear residence.
Biochim Biophys Acta Gene Regul Mech. 2017 Jun;1860(6):740-749. doi: 10.1016/j.bbagrm.2017.04.002. Epub 2017 Apr 18.
Biochim Biophys Acta Gene Regul Mech. 2017.
PMID: 28435090
Free article.
Antisense transcription of the myotonic dystrophy locus yields low-abundant RNAs with and without (CAG)n repeat.
Gudde AEEG, van Heeringen SJ, de Oude AI, van Kessel IDG, Estabrook J, Wang ET, Wieringa B, Wansink DG.
Gudde AEEG, et al. Among authors: van kessel idg.
RNA Biol. 2017 Oct 3;14(10):1374-1388. doi: 10.1080/15476286.2017.1279787. Epub 2017 Jan 19.
RNA Biol. 2017.
PMID: 28102759
Free PMC article.
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CRISPR/Cas9-Induced (CTG⋅CAG)n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.
van Agtmaal EL, André LM, Willemse M, Cumming SA, van Kessel IDG, van den Broek WJAA, Gourdon G, Furling D, Mouly V, Monckton DG, Wansink DG, Wieringa B.
van Agtmaal EL, et al. Among authors: van kessel idg.
Mol Ther. 2017 Jan 4;25(1):24-43. doi: 10.1016/j.ymthe.2016.10.014. Epub 2017 Jan 4.
Mol Ther. 2017.
PMID: 28129118
Free PMC article.
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Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophy.
González-Barriga A, Mulders SA, van de Giessen J, Hooijer JD, Bijl S, van Kessel ID, van Beers J, van Deutekom JC, Fransen JA, Wieringa B, Wansink DG.
González-Barriga A, et al.
Mol Ther Nucleic Acids. 2013 Mar 19;2(3):e81. doi: 10.1038/mtna.2013.9.
Mol Ther Nucleic Acids. 2013.
PMID: 23511335
Free PMC article.
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Cell membrane integrity in myotonic dystrophy type 1: implications for therapy.
González-Barriga A, Kranzen J, Croes HJ, Bijl S, van den Broek WJ, van Kessel ID, van Engelen BG, van Deutekom JC, Wieringa B, Mulders SA, Wansink DG.
González-Barriga A, et al.
PLoS One. 2015 Mar 23;10(3):e0121556. doi: 10.1371/journal.pone.0121556. eCollection 2015.
PLoS One. 2015.
PMID: 25799359
Free PMC article.
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Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro.
González-Barriga A, Nillessen B, Kranzen J, van Kessel IDG, Croes HJE, Aguilera B, de Visser PC, Datson NA, Mulders SAM, van Deutekom JCT, Wieringa B, Wansink DG.
González-Barriga A, et al. Among authors: van kessel idg.
Nucleic Acid Ther. 2017 Jun;27(3):144-158. doi: 10.1089/nat.2016.0641. Epub 2017 Apr 4.
Nucleic Acid Ther. 2017.
PMID: 28375678
Free PMC article.
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