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Page 1
Syntaxins 6 and 8 facilitate tau into secretory pathways.
Lee WS, Tan DC, Deng Y, van Hummel A, Ippati S, Stevens C, Carmona-Mora P, Ariawan D, Hou L, Stefen H, Tomanic T, Bi M, Tomasetig F, Martin A, Fath T, Palmer S, Ke YD, Ittner LM. Lee WS, et al. Among authors: van hummel a. Biochem J. 2021 Apr 16;478(7):1471-1484. doi: 10.1042/BCJ20200664. Biochem J. 2021. PMID: 33769438 Free PMC article.
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Ke YD, van Hummel A, Stevens CH, Gladbach A, Ippati S, Bi M, Lee WS, Krüger S, van der Hoven J, Volkerling A, Bongers A, Halliday G, Haass NK, Kiernan M, Delerue F, Ittner LM. Ke YD, et al. Among authors: van der hoven j, van hummel a. Acta Neuropathol. 2015 Nov;130(5):661-78. doi: 10.1007/s00401-015-1486-0. Epub 2015 Oct 5. Acta Neuropathol. 2015. PMID: 26437864
Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia.
Przybyla M, Stevens CH, van der Hoven J, Harasta A, Bi M, Ittner A, van Hummel A, Hodges JR, Piguet O, Karl T, Kassiou M, Housley GD, Ke YD, Ittner LM, van Eersel J. Przybyla M, et al. Among authors: van eersel j, van der hoven j, van hummel a. Neurosci Lett. 2016 Sep 19;631:24-29. doi: 10.1016/j.neulet.2016.08.007. Epub 2016 Aug 10. Neurosci Lett. 2016. PMID: 27521751
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice.
van Hummel A, Bi M, Ippati S, van der Hoven J, Volkerling A, Lee WS, Tan DC, Bongers A, Ittner A, Ke YD, Ittner LM. van Hummel A, et al. Among authors: van der hoven j. PLoS One. 2016 Oct 13;11(10):e0163236. doi: 10.1371/journal.pone.0163236. eCollection 2016. PLoS One. 2016. PMID: 27736877 Free PMC article.
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.
Ittner A, Chua SW, Bertz J, Volkerling A, van der Hoven J, Gladbach A, Przybyla M, Bi M, van Hummel A, Stevens CH, Ippati S, Suh LS, Macmillan A, Sutherland G, Kril JJ, Silva AP, Mackay JP, Poljak A, Delerue F, Ke YD, Ittner LM. Ittner A, et al. Among authors: van der hoven j, van hummel a. Science. 2016 Nov 18;354(6314):904-908. doi: 10.1126/science.aah6205. Science. 2016. PMID: 27856911
Tau exacerbates excitotoxic brain damage in an animal model of stroke.
Bi M, Gladbach A, van Eersel J, Ittner A, Przybyla M, van Hummel A, Chua SW, van der Hoven J, Lee WS, Müller J, Parmar J, Jonquieres GV, Stefen H, Guccione E, Fath T, Housley GD, Klugmann M, Ke YD, Ittner LM. Bi M, et al. Among authors: van eersel j, van der hoven j, van hummel a. Nat Commun. 2017 Sep 7;8(1):473. doi: 10.1038/s41467-017-00618-0. Nat Commun. 2017. PMID: 28883427 Free PMC article.
Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
van Hummel A, Chan G, van der Hoven J, Morsch M, Ippati S, Suh L, Bi M, Asih PR, Lee WS, Butler TA, Przybyla M, Halliday GM, Piguet O, Kiernan MC, Chung RS, Ittner LM, Ke YD. van Hummel A, et al. Among authors: van der hoven j. Am J Pathol. 2018 Jun;188(6):1447-1456. doi: 10.1016/j.ajpath.2018.03.002. Epub 2018 Mar 22. Am J Pathol. 2018. PMID: 29577934 Free article.
Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice.
Brettle M, Stefen H, Djordjevic A, Fok SYY, Chan JW, van Hummel A, van der Hoven J, Przybyla M, Volkerling A, Ke YD, Delerue F, Ittner LM, Fath T. Brettle M, et al. Among authors: van der hoven j, van hummel a. Front Mol Neurosci. 2019 Sep 27;12:231. doi: 10.3389/fnmol.2019.00231. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31611772 Free PMC article.
Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature.
Przybyla M, van Eersel J, van Hummel A, van der Hoven J, Sabale M, Harasta A, Müller J, Gajwani M, Prikas E, Mueller T, Stevens CH, Power J, Housley GD, Karl T, Kassiou M, Ke YD, Ittner A, Ittner LM. Przybyla M, et al. Among authors: van hummel a. Brain. 2020 Jun 1;143(6):1889-1904. doi: 10.1093/brain/awaa133. Brain. 2020. PMID: 32375177
18 results