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Suramin inhibits chikungunya virus replication through multiple mechanisms.
Albulescu IC, van Hoolwerff M, Wolters LA, Bottaro E, Nastruzzi C, Yang SC, Tsay SC, Hwu JR, Snijder EJ, van Hemert MJ. Albulescu IC, et al. Among authors: van hoolwerff m, van hemert mj. Antiviral Res. 2015 Sep;121:39-46. doi: 10.1016/j.antiviral.2015.06.013. Epub 2015 Jun 22. Antiviral Res. 2015. PMID: 26112648
Elucidating Epigenetic Regulation by Identifying Functional cis-Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage.
van Hoolwerff M, Metselaar PI, Tuerlings M, Suchiman HED, Lakenberg N, Ramos YFM, Cats D, Nelissen RGHH, Broekhuis D, Mei H, de Almeida RC, Meulenbelt I. van Hoolwerff M, et al. Arthritis Rheumatol. 2020 Nov;72(11):1845-1854. doi: 10.1002/art.41396. Epub 2020 Sep 24. Arthritis Rheumatol. 2020. PMID: 32840049 Free PMC article.
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.
Tuerlings M, van Hoolwerff M, Houtman E, Suchiman EHED, Lakenberg N, Mei H, van der Linden EHMJ, Nelissen RRGHH, Ramos YYFM, Coutinho de Almeida R, Meulenbelt I. Tuerlings M, et al. Among authors: van hoolwerff m. Arthritis Rheumatol. 2021 May;73(5):789-799. doi: 10.1002/art.41600. Epub 2021 Mar 21. Arthritis Rheumatol. 2021. PMID: 33258547 Free PMC article.
Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis.
Houtman E, van Hoolwerff M, Lakenberg N, Suchiman EHD, van der Linden-van der Zwaag E, Nelissen RGHH, Ramos YFM, Meulenbelt I. Houtman E, et al. Among authors: van hoolwerff m. Rheumatol Ther. 2021 Mar;8(1):499-515. doi: 10.1007/s40744-021-00287-y. Epub 2021 Feb 20. Rheumatol Ther. 2021. PMID: 33608843 Free PMC article.
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.
Coutinho de Almeida R, Ramos YFM, Mahfouz A, den Hollander W, Lakenberg N, Houtman E, van Hoolwerff M, Suchiman HED, Rodríguez Ruiz A, Slagboom PE, Mei H, Kiełbasa SM, Nelissen RGHH, Reinders M, Meulenbelt I. Coutinho de Almeida R, et al. Among authors: van hoolwerff m. Ann Rheum Dis. 2019 Feb;78(2):270-277. doi: 10.1136/annrheumdis-2018-213882. Epub 2018 Dec 1. Ann Rheum Dis. 2019. PMID: 30504444 Free PMC article.
Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis.
Tuerlings M, van Hoolwerff M, van Bokkum JM, Suchiman HED, Lakenberg N, Broekhuis D, Nelissen RGHH, Ramos YFM, Mei H, Cats D, Coutinho de Almeida R, Meulenbelt I. Tuerlings M, et al. Among authors: van hoolwerff m. Rheumatology (Oxford). 2022 Jul 6;61(7):3023-3032. doi: 10.1093/rheumatology/keab826. Rheumatology (Oxford). 2022. PMID: 34730803 Free PMC article.
Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization.
Rodríguez Ruiz A, van Hoolwerff M, Sprangers S, Suchiman E, Schoenmaker T, Dibbets-Schneider P, Bloem JL, Nelissen RGHH, Freund C, Mummery C, Everts V, de Vries TJ, Ramos YFM, Meulenbelt I. Rodríguez Ruiz A, et al. Among authors: van hoolwerff m. Rheumatology (Oxford). 2022 Dec 23;62(1):360-372. doi: 10.1093/rheumatology/keac232. Rheumatology (Oxford). 2022. PMID: 35412619 Free PMC article.
WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes.
Tuerlings M, Janssen GMC, Boone I, van Hoolwerff M, Rodriguez Ruiz A, Houtman E, Suchiman HED, van der Wal RJP, Nelissen RGHH, Coutinho de Almeida R, van Veelen PA, Ramos YFM, Meulenbelt I. Tuerlings M, et al. Among authors: van hoolwerff m. Osteoarthritis Cartilage. 2023 Jan;31(1):39-48. doi: 10.1016/j.joca.2022.09.009. Epub 2022 Oct 5. Osteoarthritis Cartilage. 2023. PMID: 36208715 Free article.
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