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IMI European Lead Factory - democratizing access to high-throughput screening.
Nat Rev Drug Discov. 2022 Apr;21(4):245-246. doi: 10.1038/d41573-021-00196-3.
Nat Rev Drug Discov. 2022.
PMID: 34907316
No abstract available.
Hit Discovery for Public Target Programs in the European Lead Factory: Experiences and Output from Assay Development and Ultra-High-Throughput Screening.
Honarnejad S, van Boeckel S, van den Hurk H, van Helden S.
Honarnejad S, et al.
SLAS Discov. 2021 Feb;26(2):192-204. doi: 10.1177/2472555220942765. Epub 2020 Jul 31.
SLAS Discov. 2021.
PMID: 32734803
Free PMC article.
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The European Lead Factory: Results from a decade of collaborative, public-private, drug discovery programs.
van Vlijmen H, Pannifer AD, Cochrane P, Basting D, Li VM, Engkvist O, Ortholand JY, Wagener M, Duffy J, Finsinger D, Davis J, van Helden SP, de Vlieger JSB; European Lead Factory Consortium.
van Vlijmen H, et al. Among authors: van helden sp.
Drug Discov Today. 2024 Mar;29(3):103886. doi: 10.1016/j.drudis.2024.103886. Epub 2024 Jan 18.
Drug Discov Today. 2024.
PMID: 38244673
Free article.
Review.
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Quantitative structure-activity relationship studies of progesterone receptor binding steroids.
So SS, van Helden SP, van Geerestein VJ, Karplus M.
So SS, et al. Among authors: van helden sp.
J Chem Inf Comput Sci. 2000 May-Jun;40(3):762-72. doi: 10.1021/ci990130v.
J Chem Inf Comput Sci. 2000.
PMID: 10850780
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The conformational behaviour of complexes of alpha-cyclodextrin with p-chlorophenol and p-hydroxybenzoic acid in water as studied by molecular dynamics simulations.
van Helden SP, van Eijck BP, Janssen LH.
van Helden SP, et al.
J Biomol Struct Dyn. 1992 Jun;9(6):1269-83. doi: 10.1080/07391102.1992.10507991.
J Biomol Struct Dyn. 1992.
PMID: 1637512
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Modeling and conformation analysis of beta-cyclodextrin complexes.
Kostense AS, van Helden SP, Janssen LH.
Kostense AS, et al. Among authors: van helden sp.
J Comput Aided Mol Des. 1991 Dec;5(6):525-43. doi: 10.1007/BF00135312.
J Comput Aided Mol Des. 1991.
PMID: 1818089
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