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The autoinflammation-associated NLRC4V341A mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice.
Eeckhout E, Asaoka T, Van Gorp H, Demon D, Girard-Guyonvarc'h C, Andries V, Vereecke L, Gabay C, Lamkanfi M, van Loo G, Wullaert A. Eeckhout E, et al. Among authors: van gorp h. Front Immunol. 2023 Nov 28;14:1272639. doi: 10.3389/fimmu.2023.1272639. eCollection 2023. Front Immunol. 2023. PMID: 38090573 Free PMC article.
Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.
Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J. Jorch SK, et al. Among authors: van gorp h. J Allergy Clin Immunol. 2023 Jul;152(1):230-243. doi: 10.1016/j.jaci.2023.01.037. Epub 2023 Feb 22. J Allergy Clin Immunol. 2023. PMID: 36822481 Free article.
An embedded interfacial network stabilizes inorganic CsPbI3 perovskite thin films.
Steele JA, Braeckevelt T, Prakasam V, Degutis G, Yuan H, Jin H, Solano E, Puech P, Basak S, Pintor-Monroy MI, Van Gorp H, Fleury G, Yang RX, Lin Z, Huang H, Debroye E, Chernyshov D, Chen B, Wei M, Hou Y, Gehlhaar R, Genoe J, De Feyter S, Rogge SMJ, Walsh A, Sargent EH, Yang P, Hofkens J, Van Speybroeck V, Roeffaers MBJ. Steele JA, et al. Among authors: van gorp h. Nat Commun. 2022 Dec 6;13(1):7513. doi: 10.1038/s41467-022-35255-9. Nat Commun. 2022. PMID: 36473874 Free PMC article.
GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis.
Chauhan D, Demon D, Vande Walle L, Paerewijck O, Zecchin A, Bosseler L, Santoni K, Planès R, Ribo S, Fossoul A, Gonçalves A, Van Gorp H, Van Opdenbosch N, Van Hauwermeiren F, Meunier E, Wullaert A, Lamkanfi M. Chauhan D, et al. Among authors: van gorp h. EMBO Rep. 2022 Oct 6;23(10):e54277. doi: 10.15252/embr.202154277. Epub 2022 Jul 28. EMBO Rep. 2022. PMID: 35899491 Free PMC article.
Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax.
Van Hauwermeiren F, Van Opdenbosch N, Van Gorp H, de Vasconcelos N, van Loo G, Vandenabeele P, Kanneganti TD, Lamkanfi M. Van Hauwermeiren F, et al. Among authors: van gorp h. Proc Natl Acad Sci U S A. 2022 Jan 11;119(2):e2116415119. doi: 10.1073/pnas.2116415119. Proc Natl Acad Sci U S A. 2022. PMID: 34996874 Free PMC article.
49 results