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A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture.
Chakrabarty S, Quiros-Solano WF, Kuijten MMP, Haspels B, Mallya S, Lo CSY, Othman A, Silvestri C, van de Stolpe A, Gaio N, Odijk H, van de Ven M, de Ridder CMA, van Weerden WM, Jonkers J, Dekker R, Taneja N, Kanaar R, van Gent DC. Chakrabarty S, et al. Among authors: van de ven m, van de stolpe a, van weerden wm, van gent dc. Cancer Res. 2022 Feb 1;82(3):510-520. doi: 10.1158/0008-5472.CAN-21-0799. Epub 2021 Dec 6. Cancer Res. 2022. PMID: 34872965 Free PMC article.
Molecular mechanisms of DNA double strand break repair.
Kanaar R, Hoeijmakers JH, van Gent DC. Kanaar R, et al. Among authors: van gent dc. Trends Cell Biol. 1998 Dec;8(12):483-9. doi: 10.1016/s0962-8924(98)01383-x. Trends Cell Biol. 1998. PMID: 9861670 Review.
Human Rad50/Mre11 is a flexible complex that can tether DNA ends.
de Jager M, van Noort J, van Gent DC, Dekker C, Kanaar R, Wyman C. de Jager M, et al. Among authors: van gent dc, van noort j. Mol Cell. 2001 Nov;8(5):1129-35. doi: 10.1016/s1097-2765(01)00381-1. Mol Cell. 2001. PMID: 11741547 Free article.
MicroRNAs, the DNA damage response and cancer.
Wouters MD, van Gent DC, Hoeijmakers JH, Pothof J. Wouters MD, et al. Among authors: van gent dc. Mutat Res. 2011 Dec 1;717(1-2):54-66. doi: 10.1016/j.mrfmmm.2011.03.012. Epub 2011 Apr 6. Mutat Res. 2011. PMID: 21477600 Review.
Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.
Naipal KA, Verkaik NS, Ameziane N, van Deurzen CH, Ter Brugge P, Meijers M, Sieuwerts AM, Martens JW, O'Connor MJ, Vrieling H, Hoeijmakers JH, Jonkers J, Kanaar R, de Winter JP, Vreeswijk MP, Jager A, van Gent DC. Naipal KA, et al. Among authors: van deurzen ch, van gent dc. Clin Cancer Res. 2014 Sep 15;20(18):4816-26. doi: 10.1158/1078-0432.CCR-14-0571. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963051
DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells.
Pont LM, Naipal K, Kloezeman JJ, Venkatesan S, van den Bent M, van Gent DC, Dirven CM, Kanaar R, Lamfers ML, Leenstra S. Pont LM, et al. Among authors: van den bent m, van gent dc. Cancer Lett. 2015 Jan 28;356(2 Pt B):525-35. doi: 10.1016/j.canlet.2014.09.049. Epub 2014 Oct 8. Cancer Lett. 2015. PMID: 25305451
112 results