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The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas.
van Wijk LM, Vermeulen S, Meijers M, van Diest MF, Ter Haar NT, de Jonge MM, Solleveld-Westerink N, van Wezel T, van Gent DC, Kroep JR, Bosse T, Gaarenstroom KN, Vrieling H, Vreeswijk MPG. van Wijk LM, et al. Among authors: van gent dc, van diest mf, van wezel t. Cancers (Basel). 2020 Sep 29;12(10):2805. doi: 10.3390/cancers12102805. Cancers (Basel). 2020. PMID: 33003546 Free PMC article.
Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.
Naipal KA, Verkaik NS, Ameziane N, van Deurzen CH, Ter Brugge P, Meijers M, Sieuwerts AM, Martens JW, O'Connor MJ, Vrieling H, Hoeijmakers JH, Jonkers J, Kanaar R, de Winter JP, Vreeswijk MP, Jager A, van Gent DC. Naipal KA, et al. Among authors: van deurzen ch, van gent dc. Clin Cancer Res. 2014 Sep 15;20(18):4816-26. doi: 10.1158/1078-0432.CCR-14-0571. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963051
Tumor slice culture system to assess drug response of primary breast cancer.
Naipal KA, Verkaik NS, Sánchez H, van Deurzen CH, den Bakker MA, Hoeijmakers JH, Kanaar R, Vreeswijk MP, Jager A, van Gent DC. Naipal KA, et al. Among authors: van deurzen ch, van gent dc. BMC Cancer. 2016 Feb 9;16:78. doi: 10.1186/s12885-016-2119-2. BMC Cancer. 2016. PMID: 26860465 Free PMC article.
Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.
Meijer TG, Nguyen L, Van Hoeck A, Sieuwerts AM, Verkaik NS, Ladan MM, Ruigrok-Ritstier K, van Deurzen CHM, van de Werken HJG, Lips EH, Linn SC, Memari Y, Davies H, Nik-Zainal S, Kanaar R, Martens JWM, Cuppen E, Jager A, van Gent DC. Meijer TG, et al. Among authors: van gent dc. Oncogene. 2022 Jun;41(26):3498-3506. doi: 10.1038/s41388-022-02363-1. Epub 2022 Jun 3. Oncogene. 2022. PMID: 35662281 Free PMC article.
Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma.
Capala ME, Pachler KS, Lauwers I, de Korte MA, Verkaik NS, Mast H, Jonker BP, Sewnaik A, Hardillo JA, Keereweer S, Monserez D, Koljenovic S, Mostert B, Verduijn GM, Petit S, van Gent DC. Capala ME, et al. Among authors: van gent dc. Cancers (Basel). 2023 Jan 12;15(2):478. doi: 10.3390/cancers15020478. Cancers (Basel). 2023. PMID: 36672427 Free PMC article.
Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
Meijer TG, Martens JWM, Prager-van der Smissen WJC, Verkaik NS, Beaufort CM, van Herk S, Robert-Finestra T, Hoogenboezem RM, Ruigrok-Ritstier K, Paul MW, Gribnau J, Bindels EMJ, Kanaar R, Jager A, van Gent DC, Hollestelle A. Meijer TG, et al. Among authors: van gent dc. Cancers (Basel). 2024 Feb 10;16(4):741. doi: 10.3390/cancers16040741. Cancers (Basel). 2024. PMID: 38398132 Free PMC article.
112 results