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Disease variants alter transcription factor levels and methylation of their binding sites.
Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium; Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT. Bonder MJ, et al. Among authors: van t hof p, van duijn cm, van heemst d, van dijk f, van den berg lh, van rooij j, van meurs jb, van dongen j, van der kallen cj, van der breggen r, van iterson m, van zwet ew, van greevenbroek mm, van galen m. Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5. Nat Genet. 2017. PMID: 27918535
The continuing value of twin studies in the omics era.
van Dongen J, Slagboom PE, Draisma HH, Martin NG, Boomsma DI. van Dongen J, et al. Nat Rev Genet. 2012 Sep;13(9):640-53. doi: 10.1038/nrg3243. Epub 2012 Jul 31. Nat Rev Genet. 2012. PMID: 22847273 Review.
Sex differences in genetic architecture of complex phenotypes?
Vink JM, Bartels M, van Beijsterveldt TC, van Dongen J, van Beek JH, Distel MA, de Moor MH, Smit DJ, Minica CC, Ligthart L, Geels LM, Abdellaoui A, Middeldorp CM, Hottenga JJ, Willemsen G, de Geus EJ, Boomsma DI. Vink JM, et al. Among authors: van beek jh, van beijsterveldt tc, van dongen j. PLoS One. 2012;7(12):e47371. doi: 10.1371/journal.pone.0047371. Epub 2012 Dec 18. PLoS One. 2012. PMID: 23272036 Free PMC article.
The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection.
Willemsen G, Vink JM, Abdellaoui A, den Braber A, van Beek JH, Draisma HH, van Dongen J, van 't Ent D, Geels LM, van Lien R, Ligthart L, Kattenberg M, Mbarek H, de Moor MH, Neijts M, Pool R, Stroo N, Kluft C, Suchiman HE, Slagboom PE, de Geus EJ, Boomsma DI. Willemsen G, et al. Among authors: van beek jh, van lien r, van t ent d, van dongen j. Twin Res Hum Genet. 2013 Feb;16(1):271-81. doi: 10.1017/thg.2012.140. Epub 2013 Jan 8. Twin Res Hum Genet. 2013. PMID: 23298648 Free PMC article.
1,252 results