van Dinther M - Search Results

1

Role of soluble endoglin in BMP9 signaling.

Lawera A, Tong Z, Thorikay M, Redgrave RE, Cai J, van Dinther M, Morrell NW, Afink GB, Charnock-Jones DS, Arthur HM, Ten Dijke P, Li W. Lawera A, et al. Among authors: van dinther m. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17800-17808. doi: 10.1073/pnas.1816661116. Epub 2019 Aug 20. Proc Natl Acad Sci U S A. 2019. PMID: 31431534 Free PMC article.

2

RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta.

Piek E, Van Dinther M, Parks WT, Sallee JM, Böttinger EP, Roberts AB, Ten Dijke P. Piek E, et al. Among authors: van dinther m. Biochem J. 2004 Oct 1;383(Pt 1):187-99. doi: 10.1042/BJ20040774. Biochem J. 2004. PMID: 15239668 Free PMC article.

3

The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.

Deckers M, van Dinther M, Buijs J, Que I, Löwik C, van der Pluijm G, ten Dijke P. Deckers M, et al. Among authors: van der pluijm g, van dinther m. Cancer Res. 2006 Feb 15;66(4):2202-9. doi: 10.1158/0008-5472.CAN-05-3560. Cancer Res. 2006. PMID: 16489022

4

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis.

Scharpfenecker M, van Dinther M, Liu Z, van Bezooijen RL, Zhao Q, Pukac L, Löwik CW, ten Dijke P. Scharpfenecker M, et al. Among authors: van dinther m, van bezooijen rl. J Cell Sci. 2007 Mar 15;120(Pt 6):964-72. doi: 10.1242/jcs.002949. Epub 2007 Feb 20. J Cell Sci. 2007. PMID: 17311849

5

Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis.

Petersen M, Thorikay M, Deckers M, van Dinther M, Grygielko ET, Gellibert F, de Gouville AC, Huet S, ten Dijke P, Laping NJ. Petersen M, et al. Among authors: van dinther m. Kidney Int. 2008 Mar;73(6):705-15. doi: 10.1038/sj.ki.5002717. Epub 2007 Dec 12. Kidney Int. 2008. PMID: 18075500 Free article.

6

Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish.

Monteiro R, van Dinther M, Bakkers J, Wilkinson R, Patient R, ten Dijke P, Mummery C. Monteiro R, et al. Among authors: van dinther m. Dev Biol. 2008 Mar 1;315(1):55-71. doi: 10.1016/j.ydbio.2007.11.038. Epub 2007 Dec 15. Dev Biol. 2008. PMID: 18222420 Free article.

7

VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

Liu Z, Kobayashi K, van Dinther M, van Heiningen SH, Valdimarsdottir G, van Laar T, Scharpfenecker M, Löwik CW, Goumans MJ, Ten Dijke P, Pardali E. Liu Z, et al. Among authors: van laar t, van dinther m, van heiningen sh. J Cell Sci. 2009 Sep 15;122(Pt 18):3294-302. doi: 10.1242/jcs.048942. Epub 2009 Aug 25. J Cell Sci. 2009. PMID: 19706683

8

ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation.

van Dinther M, Visser N, de Gorter DJ, Doorn J, Goumans MJ, de Boer J, ten Dijke P. van Dinther M, et al. J Bone Miner Res. 2010 Jun;25(6):1208-15. doi: 10.1359/jbmr.091110. J Bone Miner Res. 2010. PMID: 19929436 Free article.

9

Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation.

Herrera B, van Dinther M, Ten Dijke P, Inman GJ. Herrera B, et al. Among authors: van dinther m. Cancer Res. 2009 Dec 15;69(24):9254-62. doi: 10.1158/0008-5472.CAN-09-2912. Cancer Res. 2009. PMID: 19996292 Free PMC article.

10

Measurement of constitutive activity of BMP type I receptors.

de Gorter DJ, van Dinther M, Ten Dijke P. de Gorter DJ, et al. Among authors: van dinther m. Methods Enzymol. 2010;484:281-93. doi: 10.1016/B978-0-12-381298-8.00015-0. Methods Enzymol. 2010. PMID: 21036238

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