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Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck.
de Boer DV, Martens-de Kemp SR, Buijze M, Stigter-van Walsum M, Bloemena E, Dietrich R, Leemans CR, van Beusechem VW, Braakhuis BJM, Brakenhoff RH. de Boer DV, et al. Among authors: van beusechem vw. Oncotarget. 2017 May 16;8(58):97928-97940. doi: 10.18632/oncotarget.17880. eCollection 2017 Nov 17. Oncotarget. 2017. PMID: 29228663 Free PMC article.
Adenovirus retargeting to surface expressed antigens on oral mucosa.
van Zeeburg HJ, van Beusechem VW, Huizenga A, Haisma HJ, Korokhov N, Gibbs S, Leemans CR, Brakenhoff RH. van Zeeburg HJ, et al. Among authors: van beusechem vw. J Gene Med. 2010 Apr;12(4):365-76. doi: 10.1002/jgm.1447. J Gene Med. 2010. PMID: 20373331
Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin.
Posthumadeboer J, van Egmond PW, Helder MN, de Menezes RX, Cleton-Jansen AM, Beliën JA, Verheul HM, van Royen BJ, Kaspers GJ, van Beusechem VW. Posthumadeboer J, et al. Among authors: van royen bj, van egmond pw, van beusechem vw. Oncotarget. 2012 Oct;3(10):1169-81. doi: 10.18632/oncotarget.600. Oncotarget. 2012. PMID: 23045411 Free PMC article.
Genome-wide siRNA Screen Identifies the Radiosensitizing Effect of Downregulation of MASTL and FOXM1 in NSCLC.
Nagel R, Stigter-van Walsum M, Buijze M, van den Berg J, van der Meulen IH, Hodzic J, Piersma SR, Pham TV, Jiménez CR, van Beusechem VW, Brakenhoff RH. Nagel R, et al. Among authors: van den berg j, van der meulen ih, van beusechem vw. Mol Cancer Ther. 2015 Jun;14(6):1434-44. doi: 10.1158/1535-7163.MCT-14-0846. Epub 2015 Mar 25. Mol Cancer Ther. 2015. PMID: 25808837
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.
de Lange J, Faramarz A, Oostra AB, de Menezes RX, van der Meulen IH, Rooimans MA, Rockx DA, Brakenhoff RH, van Beusechem VW, King RW, de Winter JP, Wolthuis RMF. de Lange J, et al. Among authors: van der meulen ih, van beusechem vw. Nat Commun. 2015 Oct 1;6:8399. doi: 10.1038/ncomms9399. Nat Commun. 2015. PMID: 26423134 Free PMC article.
The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics.
Martens-de Kemp SR, Brink A, van der Meulen IH, de Menezes RX, Te Beest DE, Leemans CR, van Beusechem VW, Braakhuis BJ, Brakenhoff RH. Martens-de Kemp SR, et al. Among authors: van der meulen ih, van beusechem vw. Mol Cancer Ther. 2017 Mar;16(3):540-550. doi: 10.1158/1535-7163.MCT-16-0457. Epub 2016 Dec 15. Mol Cancer Ther. 2017. PMID: 27980104
Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection.
Bachas C, Hodzic J, van der Mijn JC, Stoepker C, Verheul HMW, Wolthuis RMF, Felley-Bosco E, van Wieringen WN, van Beusechem VW, Brakenhoff RH, de Menezes RX. Bachas C, et al. Among authors: van der mijn jc, van wieringen wn, van beusechem vw. BMC Bioinformatics. 2018 Aug 20;19(1):301. doi: 10.1186/s12859-018-2306-z. BMC Bioinformatics. 2018. PMID: 30126372 Free PMC article.
115 results