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32 results

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Mind shift I: Fructus Aurantii - Rhizoma Chuanxiong synergistically anchors stress-induced depression-like behaviours and gastrointestinal dysmotility cluster by regulating psycho-immune-neuroendocrine network.
Liu X, Luo M, Wang Z, Yang SJ, Su M, Wang Y, Wang W, Sun Z, Cai Y, Wu L, Zhou R, Xu M, Zhao Q, Chen L, Zuo W, Huang Y, Ren P, Huang X. Liu X, et al. Phytomedicine. 2024 Jun;128:155324. doi: 10.1016/j.phymed.2023.155324. Epub 2023 Dec 30. Phytomedicine. 2024. PMID: 38552437
METHODS/RESULTS: Here, Rhizoma Chuanxiong, one of the seven components of Chaihu-shugan-San, elicited the best antidepressant effect on CUMS rats, followed by Fructus Aurantii. ...
METHODS/RESULTS: Here, Rhizoma Chuanxiong, one of the seven components of Chaihu-shugan-San, elicited the best antidepressant effect …
Natural products derived from herbs as promising source for diarrhea predominant-irritable bowel syndrome via gut microbiota-serotonin pathway.
Zhang M, Dang M, Li Y, Wei P, Zhao C, Dong T. Zhang M, et al. J Pharm Pharmacol. 2024 Jan 10:rgad120. doi: 10.1093/jpp/rgad120. Online ahead of print. J Pharm Pharmacol. 2024. PMID: 38198750
It further accelerated gastrointestinal motility and visceral hyperalgesia. Herbal medicine prescription including Tongxie yaofang and Shugan decoction, as well as some monomers of flavonoid and polyphenol compounds can be regarded as the potential agents for IBS-D. ...
It further accelerated gastrointestinal motility and visceral hyperalgesia. Herbal medicine prescription including Tongxie yaofang and Sh …
Corrigendum to "Clinical efficacy of Shugan granule in the treatment of mixed anxiety-depressive disorder: A multicenter, randomized, double-blind, placebo-controlled trial" [J. Ethnopharmacol. 290 (2022) 115032].
Li Y, Li L, Guo R, Yu H, Wang X, Wang B, Wang Q, Li Z, Zhao H, Temu Q, Chen X, Zhang Y, An J, Cai X, Li A, Qi L, Shang J, He H, Yang D, Lin J, Zhang Y, Zou T. Li Y, et al. J Ethnopharmacol. 2024 Jan 30;319(Pt 1):117370. doi: 10.1016/j.jep.2023.117370. Epub 2023 Nov 3. J Ethnopharmacol. 2024. PMID: 37923593 No abstract available.
[Antidepressant mechanism of Shenling Kaixin Granules based on BDNF/TrkB/CREB pathway].
Xu Y, Liu DG, Ning TB, Zhu JG, Yao R, Meng X, Yao JC, Zhao WX. Xu Y, et al. Zhongguo Zhong Yao Za Zhi. 2023 Apr;48(8):2184-2192. doi: 10.19540/j.cnki.cjcmm.20221114.402. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 37282906 Chinese.
Ninety male SD rats were randomly divided into control group, model group, Shugan Jieyu Capsules(110 mg.kg~(-1)) group and SLKX low-(90 mg.kg~(-1)), medium-(180 mg.kg~(-1)), and high-dose(360 mg.kg~(-1)) groups. ...
Ninety male SD rats were randomly divided into control group, model group, Shugan Jieyu Capsules(110 mg.kg~(-1)) group and SLKX low-( …
[Study on protective effect of Chaihu Shugan Powder against liver injury in rats with intrahepatic cholestasis by regulating FXR/Nrf2/ARE pathway].
Lou J, Zhao L, Zhu YJ, Yuan SQ, Wang F, Zhang HZ, Xu JJ, Yu XK, Hou LF. Lou J, et al. Zhongguo Zhong Yao Za Zhi. 2022 Oct;47(20):5610-5616. doi: 10.19540/j.cnki.cjcmm.20220519.401. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 36471979 Chinese.
This study aims to investigate the effect of Chaihu Shugan Powder(CHSG) on liver injury in rats with intrahepatic cholestasis by regulating farnesoid X receptor(FXR)/nuclear factor erythroid-2-related factor(Nrf2)/antioxidant response element(ARE) pathway. ...
This study aims to investigate the effect of Chaihu Shugan Powder(CHSG) on liver injury in rats with intrahepatic cholestasis by regu …
Modified Sijunzi granule decreases post-weaning diarrhea in Rex rabbits via promoting intestinal development.
Li D, Wang Y, Liu N, Chen S, Liu H, Wang P, Yu Z, Shu G, Lin J, Zhang W, Peng G, Zhao L, Tang H, Zhang K, Wen B, Fu H. Li D, et al. Front Vet Sci. 2022 Nov 7;9:972326. doi: 10.3389/fvets.2022.972326. eCollection 2022. Front Vet Sci. 2022. PMID: 36419729 Free PMC article.
Traditional Chinese medicine (TCM) formulas can be adjusted on the basis of TCM basic theory to achieve the best curative effect, especially for diseases with complex pathogenesis, such as post-weaning diarrhea (PWD). Shugan Jianwei Sijunzi decoction (SJ-SJZD) can be recog …
Traditional Chinese medicine (TCM) formulas can be adjusted on the basis of TCM basic theory to achieve the best curative effect, especially …
Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation.
Lei S, Zhao S, Huang X, Feng Y, Li Z, Chen L, Huang P, Guan H, Zhang H, Wu Q, Chen B. Lei S, et al. Front Pharmacol. 2022 Sep 12;13:967623. doi: 10.3389/fphar.2022.967623. eCollection 2022. Front Pharmacol. 2022. PMID: 36172180 Free PMC article.
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic disease and is intertwined with cardiovascular disorders and diabetes. Chaihu Shugan powder (CSP) is a traditional Chinese medicine with a significant therapeutic effect on metabolic diseases …
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic disease and is intertwined with cardiovascular disorders a …
SIRT1/FOXO1 Axis-Mediated Hippocampal Angiogenesis is Involved in the Antidepressant Effect of Chaihu Shugan San.
Zhang S, Lu Y, Shi W, Ren Y, Xiao K, Chen W, Li L, Zhao J. Zhang S, et al. Drug Des Devel Ther. 2022 Aug 23;16:2783-2801. doi: 10.2147/DDDT.S370825. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36039087 Free PMC article.
OBJECTIVE: Chaihu Shugan San (CSS) has a long history for treating major depressive disorder (MDD), which has been verified effectively and safely in clinical studies. ...
OBJECTIVE: Chaihu Shugan San (CSS) has a long history for treating major depressive disorder (MDD), which has been verified effective …
Comparison on different traditional Chinese medicine therapies for chronic hepatitis B liver fibrosis.
Dai YK, Fan HN, Hu YH, Zhao ZM, Liu C. Dai YK, et al. Front Pharmacol. 2022 Aug 10;13:943063. doi: 10.3389/fphar.2022.943063. eCollection 2022. Front Pharmacol. 2022. PMID: 36034853 Free PMC article.
Results of SUCRA value rankings indicated that Fuzheng Huayu therapy or combined with entecavir had preferable effects in improving the clinical efficacy, recovering the level of hyaluronic acid, IV-C, ALT, ALB, and TBil, relieving the TCM symptoms including hypochondriac pain an …
Results of SUCRA value rankings indicated that Fuzheng Huayu therapy or combined with entecavir had preferable effects in improving the clin …
Tandem Mass Tag Analysis of the Effect of the Anterior Cingulate Cortex in Nonerosive Reflux Disease Rats with Shugan Jiangni Hewei Granules Treatment.
Wang T, Li J, Jia Y, Zhao J, He M, Bai G. Wang T, et al. Comput Math Methods Med. 2022 Jul 30;2022:8104337. doi: 10.1155/2022/8104337. eCollection 2022. Comput Math Methods Med. 2022. PMID: 35941898 Free PMC article.
OBJECTIVE: The current study aims to analyze the improvement mechanism of visceral hypersensitivity (VH) and targets of Shugan Jiangni Hewei granules (SJHG) for nonerosive reflux disease (NERD) treatment as well as to offer an experimental foundation for its clinical use. …
OBJECTIVE: The current study aims to analyze the improvement mechanism of visceral hypersensitivity (VH) and targets of Shugan Jiangn …
32 results