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158 results

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Page 1
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts.
Ji J, Dragojevic S, Callaghan CM, Smith EJ, Talele S, Zhang W, Connors MA, Mladek AC, Hu Z, Bakken KK, Sarkaria PP, Carlson BL, Burgenske DM, Decker PA, Rashid MA, Jang MH, Gupta SK, Eckel-Passow JE, Elmquist WF, Sarkaria JN. Ji J, et al. Mol Cancer Ther. 2024 May 2;23(5):662-671. doi: 10.1158/1535-7163.MCT-23-0552. Mol Cancer Ther. 2024. PMID: 38224566 Free PMC article.
In clonogenic survival assays, peposertib augmented radiation-induced killing of M12 cells at concentrations 100 nmol/L, and a minimum of 16 hours exposure allowed maximal sensitization. ...
In clonogenic survival assays, peposertib augmented radiation-induced killing of M12 cells at concentrations 100 nmol/L, and a minimu …
Dopamine levels determined in synthetic urine using an electrochemical tyrosinase biosensor based on ZnO@Au core-shell.
Beatto TG, Gomes WE, Etchegaray A, Gupta R, Mendes RK. Beatto TG, et al. RSC Adv. 2023 Nov 14;13(47):33424-33429. doi: 10.1039/d3ra06277e. eCollection 2023 Nov 7. RSC Adv. 2023. PMID: 38025875 Free PMC article.
The limit of detection and dynamic range of the biosensor for dopamine in real samples were 86 nmol L(-1) and 0.1 to 500 mumol L(-1), respectively. Thus, the results indicate that the proposed miniaturized biosensor device is promising for the monitoring of dopamine in rea …
The limit of detection and dynamic range of the biosensor for dopamine in real samples were 86 nmol L(-1) and 0.1 to 500 mumol L(-1), …
Normative range of various serum hormonal parameters among Indian women of reproductive age: ICMR-PCOS task force study outcome.
Ganie MA, Chowdhury S, Suri V, Joshi B, Bhattacharya PK, Agrawal S, Malhotra N, Sahay R, Jabbar PK, Nair A, Rozati R, Shukla A, Rashid R, Shah IA, Rashid H, Wani IA, Arora T, Kulkarni B; PCOS Study Group. Ganie MA, et al. Lancet Reg Health Southeast Asia. 2023 May 30;15:100226. doi: 10.1016/j.lansea.2023.100226. eCollection 2023 Aug. Lancet Reg Health Southeast Asia. 2023. PMID: 37614351 Free PMC article.
In the present study, the biological reference interval (2.5th-97.5th centile) observed were: serum T4: mug/dL (5.23-12.31), TSH: mug/mL (0.52-4.16) and serum prolactin: ng/mL (5.13-37.35), LH: mIU/mL (2.75-20.68), FSH: mIU/mL 2.59-15.12), serum total testosterone: ng/mL (0.06-0. …
In the present study, the biological reference interval (2.5th-97.5th centile) observed were: serum T4: mug/dL (5.23-12.31), TSH: mug/mL (0. …
Surface Functional Groups Affect Iron (Hydr)oxide Heterogeneous Nucleation: Implications for Membrane Scaling.
Chou PI, Ghim D, Gupta P, Singamaneni S, Lee B, Jun YS. Chou PI, et al. Environ Sci Technol. 2023 Aug 1;57(30):11056-11066. doi: 10.1021/acs.est.3c01528. Epub 2023 Jul 19. Environ Sci Technol. 2023. PMID: 37467155
Moreover, on the OH-surface, the high functional group density of 0.76 nmol/cm(2) caused faster heterogeneous nucleation than that on a COOH-surface, with a density of 0.28 0.04 nmol/cm(2). ...
Moreover, on the OH-surface, the high functional group density of 0.76 nmol/cm(2) caused faster heterogeneous nucleation than that on …
Assessing the role of ACC deaminase-producing bacteria in alleviating salinity stress and enhancing zinc uptake in plants by altering the root architecture of French bean (Phaseolus vulgaris) plants.
Gupta S, Pandey S, Kotra V, Kumar A. Gupta S, et al. Planta. 2023 May 22;258(1):3. doi: 10.1007/s00425-023-04159-3. Planta. 2023. PMID: 37212904
Both the strains were characterized for ACC utilization activity (426.23 and 380.54 nmol alpha-ketobutyrate mg protein(-1) h(-1)), indole acetic acid (IAA) production, phosphate solubilization, ammonia, hydrogen cyanide (HCN), and siderophore production. ...
Both the strains were characterized for ACC utilization activity (426.23 and 380.54 nmol alpha-ketobutyrate mg protein(-1) h(-1)), in …
Late-night salivary cortisol cut-offs for diagnosis of Cushing syndrome using second-generation electrochemiluminescence immunoassay kits.
Goyal A, Attri B, Gupta Y, Kalaivani M, Jyotsna VP, Tandon N. Goyal A, et al. Clin Endocrinol (Oxf). 2023 Jul;99(1):43-51. doi: 10.1111/cen.14920. Epub 2023 Apr 19. Clin Endocrinol (Oxf). 2023. PMID: 37052382
We also reviewed records of adults with endogenous CS (cases, n = 92) and a valid LNSC result using the same method. RESULTS: The 95th percentile for LNSC in controls was 6.76 nmol/L. The mean SD LNSC levels were 40.47 49.63 nmol/L in cases and 3.37 1.18 nmol …
We also reviewed records of adults with endogenous CS (cases, n = 92) and a valid LNSC result using the same method. RESULTS: The 95th perce …
Evaluation of lipoprotein(a) in the prevention and management of atherosclerotic cardiovascular disease: A survey among the Lipid Clinics Network.
Catapano AL, Tokgözoğlu L, Banach M, Gazzotti M, Olmastroni E, Casula M, Ray KK; Lipid Clinics Network Group. Catapano AL, et al. Atherosclerosis. 2023 Apr;370:5-11. doi: 10.1016/j.atherosclerosis.2023.02.007. Epub 2023 Feb 23. Atherosclerosis. 2023. PMID: 36894469
Among those who declared to routinely measure Lp(a), the Lp(a) measurement is mostly requested to further stratify patients' cardiovascular risk, and half of them recognized 50 mg/dL (approx. 110 nmol/L) as the threshold for increased cardiovascular risk due. CONCLUSIONS: …
Among those who declared to routinely measure Lp(a), the Lp(a) measurement is mostly requested to further stratify patients' cardiovascular …
ACC Deaminase Produced by PGPR Mitigates the Adverse Effect of Osmotic and Salinity Stresses in Pisum sativum through Modulating the Antioxidants Activities.
Gupta A, Rai S, Bano A, Sharma S, Kumar M, Binsuwaidan R, Suhail Khan M, Upadhyay TK, Alshammari N, Saeed M, Pathak N. Gupta A, et al. Plants (Basel). 2022 Dec 7;11(24):3419. doi: 10.3390/plants11243419. Plants (Basel). 2022. PMID: 36559529 Free PMC article.
Bacterial isolates GKP KS2_7 (Pseudomonas aeruginosa) and MBD 133 (Bacillus subtilis) could degrade ACC into alpha-ketobutyrate, exhibiting ACCD activity producing more than ~257 nmol of alpha-ketobutyrate mg protein1 h1, and were evaluated for other plant growth-promoting …
Bacterial isolates GKP KS2_7 (Pseudomonas aeruginosa) and MBD 133 (Bacillus subtilis) could degrade ACC into alpha-ketobutyrate, exhibiting …
Gallium-68-labeled Peptide PET Quantifies Tumor Exposure of PD-L1 Therapeutics.
Mishra A, Kumar D, Gupta K, Lofland G, Sharma AK, Banka DS, Hobbs RF, Dannals RF, Rowe SP, Gabrielson E, Nimmagadda S. Mishra A, et al. Clin Cancer Res. 2023 Feb 1;29(3):581-591. doi: 10.1158/1078-0432.CCR-22-1931. Clin Cancer Res. 2023. PMID: 36449662 Free PMC article.
We then quantified baseline and accessible PD-L1 levels in tumors as a noninvasive pharmacodynamic measure to assess tumor exposure to two aPD-L1 antibodies (avelumab and durvalumab). RESULTS: DK223 exhibited a KD of 1.010.83 nmol/L for PD-L1 and inhibited the PD-1:PD-L1 i …
We then quantified baseline and accessible PD-L1 levels in tumors as a noninvasive pharmacodynamic measure to assess tumor exposure to two a …
Demystifying the Relevance of Size Amongst Macro- and Micro-Corticotropinoma: Experience in 206 Patients.
Gupta R, Jain N, Bhansali A, Bhadada SK, Walia R. Gupta R, et al. Indian J Endocrinol Metab. 2022 May-Jun;26(3):275-281. doi: 10.4103/ijem.ijem_134_22. Epub 2022 Aug 4. Indian J Endocrinol Metab. 2022. PMID: 36248045 Free PMC article.
They also had a higher ACTH (139 vs. 65.8 pg/ml), 0800h cortisol (1200 vs. 880 nmol/l), 2300h cortisol (1100 vs. 700 nmol/l) and cortisol levels after high dose dexamethasone suppression test (1050 vs. 244.5 nmol/l). ...
They also had a higher ACTH (139 vs. 65.8 pg/ml), 0800h cortisol (1200 vs. 880 nmol/l), 2300h cortisol (1100 vs. 700 nmol/l) a …
158 results