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Circulating Exhausted PD-1+CD39+ Helper CD4 T Cells Are Tumor-Antigen-Specific and Predict Response to PD-1/PD-L1 Axis Blockade.
Martinez-Gomez C, Michelas M, Scarlata CM, Salvioni A, Gomez-Roca C, Sarradin V, Lauzéral-Vizcaino F, Féliu V, Dupret-Bories A, Ferron G, Sarini J, Devaud C, Delord JP, Balança CC, Martinez A, Ayyoub M. Martinez-Gomez C, et al. Cancers (Basel). 2022 Jul 28;14(15):3679. doi: 10.3390/cancers14153679. Cancers (Basel). 2022. PMID: 35954341 Free PMC article.
SHP2 Targets ITK Downstream of PD-1 to Inhibit T Cell Function.
Strazza M, Adam K, Lerrer S, Straube J, Sandigursky S, Ueberheide B, Mor A. Strazza M, et al. Inflammation. 2021 Aug;44(4):1529-1539. doi: 10.1007/s10753-021-01437-8. Epub 2021 Feb 24. Inflammation. 2021. PMID: 33624224 Free PMC article.