le Coutre PD - Search Results

1

Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.

Cortes JE, Kim DW, Pinilla-Ibarz J, le Coutre PD, Paquette R, Chuah C, Nicolini FE, Apperley JF, Khoury HJ, Talpaz M, DeAngelo DJ, Abruzzese E, Rea D, Baccarani M, Müller MC, Gambacorti-Passerini C, Lustgarten S, Rivera VM, Haluska FG, Guilhot F, Deininger MW, Hochhaus A, Hughes TP, Shah NP, Kantarjian HM. Cortes JE, et al. Among authors: le coutre pd. Blood. 2018 Jul 26;132(4):393-404. doi: 10.1182/blood-2016-09-739086. Epub 2018 Mar 22. Blood. 2018. PMID: 29567798 Free PMC article. Clinical Trial.

2

In vitro transcription and translation inhibition by anti-promyelocytic leukemia (PML)/retinoic acid receptor alpha and anti-PML peptide nucleic acid.

Gambacorti-Passerini C, Mologni L, Bertazzoli C, le Coutre P, Marchesi E, Grignani F, Nielsen PE. Gambacorti-Passerini C, et al. Blood. 1996 Aug 15;88(4):1411-7. Blood. 1996. PMID: 8695861 Free article.

3

Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis.

Gambacorti-Passerini C, le Coutre P, Mologni L, Fanelli M, Bertazzoli C, Marchesi E, Di Nicola M, Biondi A, Corneo GM, Belotti D, Pogliani E, Lydon NB. Gambacorti-Passerini C, et al. Blood Cells Mol Dis. 1997 Dec;23(3):380-94. doi: 10.1006/bcmd.1997.0155. Blood Cells Mol Dis. 1997. PMID: 9446752

4

Additive antisense effects of different PNAs on the in vitro translation of the PML/RARalpha gene.

Mologni L, leCoutre P, Nielsen PE, Gambacorti-Passerini C. Mologni L, et al. Nucleic Acids Res. 1998 Apr 15;26(8):1934-8. doi: 10.1093/nar/26.8.1934. Nucleic Acids Res. 1998. PMID: 9518485 Free PMC article.

5

In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor.

le Coutre P, Mologni L, Cleris L, Marchesi E, Buchdunger E, Giardini R, Formelli F, Gambacorti-Passerini C. le Coutre P, et al. J Natl Cancer Inst. 1999 Jan 20;91(2):163-8. doi: 10.1093/jnci/91.2.163. J Natl Cancer Inst. 1999. PMID: 9923858

6

Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification.

le Coutre P, Tassi E, Varella-Garcia M, Barni R, Mologni L, Cabrita G, Marchesi E, Supino R, Gambacorti-Passerini C. le Coutre P, et al. Blood. 2000 Mar 1;95(5):1758-66. Blood. 2000. PMID: 10688835 Free article.

7

Determination of alpha-1 acid glycoprotein in patients with Ph+ chronic myeloid leukemia during the first 13 weeks of therapy with STI571.

le Coutre P, Kreuzer KA, Na IK, Lupberger J, Holdhoff M, Appelt C, Schwarz M, Müller C, Gambacorti-Passerini C, Platzbecker U, Bonnet R, Ehninger G, Schmidt CA. le Coutre P, et al. Blood Cells Mol Dis. 2002 Jan-Feb;28(1):75-85. doi: 10.1006/bcmd.2002.0493. Blood Cells Mol Dis. 2002. PMID: 11987244

8

Binding of imatinib by alpha(1)-acid glycoprotein.

Gambacorti-Passerini C, le Coutre P, Zucchetti M, D'Incalci M. Gambacorti-Passerini C, et al. Blood. 2002 Jul 1;100(1):367-8; author reply 368-9. doi: 10.1182/blood-2002-02-0518. Blood. 2002. PMID: 12096719 Free article. No abstract available.

9

Imatinib in Philadelphia chromosome-positive chronic phase CML patients: molecular and cytogenetic response rates and prediction of clinical outcome.

Le Coutre P, Kreuzer KA, Na IK, Schwarz M, Lupberger J, Holdhoff M, Baskaynak G, Gschaidmeier H, Platzbecker U, Ehninger G, Prejzner W, Huhn D, Schmidt CA. Le Coutre P, et al. Am J Hematol. 2003 Aug;73(4):249-55. doi: 10.1002/ajh.10364. Am J Hematol. 2003. PMID: 12879428 Free article.

10

Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance.

Kantarjian HM, Giles F, Gattermann N, Bhalla K, Alimena G, Palandri F, Ossenkoppele GJ, Nicolini FE, O'Brien SG, Litzow M, Bhatia R, Cervantes F, Haque A, Shou Y, Resta DJ, Weitzman A, Hochhaus A, le Coutre P. Kantarjian HM, et al. Blood. 2007 Nov 15;110(10):3540-6. doi: 10.1182/blood-2007-03-080689. Epub 2007 Aug 22. Blood. 2007. PMID: 17715389 Free article. Clinical Trial.

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