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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 1
1990 1
1991 1
1992 7
1993 8
1994 9
1995 11
1996 14
1997 32
1998 33
1999 34
2000 53
2001 72
2002 132
2003 142
2004 165
2005 207
2006 246
2007 301
2008 281
2009 237
2010 271
2011 344
2012 330
2013 309
2014 248
2015 206
2016 163
2017 144
2018 124
2019 117
2020 107
2021 116
2022 112
2023 80
2024 43

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3,957 results

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Page 1
In Vitro Determination of Temperature-Dependent DNA Binding of the Evening Complex Using Electrophoretic Mobility Shift Assays.
Hutin S, Wigge PA, Zubieta C. Hutin S, et al. Methods Mol Biol. 2024;2795:135-147. doi: 10.1007/978-1-0716-3814-9_14. Methods Mol Biol. 2024. PMID: 38594535
Electrophoretic mobility shift assays (EMSAs) of DNA-binding proteins and labeled DNA allow the qualitative and quantitative characterization of protein-DNA complex formation using native (nondenaturing) polyacrylamide or agarose gel electrophoresis. ...
Electrophoretic mobility shift assays (EMSAs) of DNA-binding proteins and labeled DNA allow the qualitative and quantit …
Mechanistic and biophysical characterization of polymyxin resistance response regulator PmrA in Acinetobacter baumannii.
Ouyang Z, He W, Jiao M, Yu Q, Guo Y, Refat M, Qin Q, Zhang J, Shi Q, Zheng F, Wen Y. Ouyang Z, et al. Front Microbiol. 2024 Feb 27;15:1293990. doi: 10.3389/fmicb.2024.1293990. eCollection 2024. Front Microbiol. 2024. PMID: 38476937 Free PMC article.
METHODS: X-ray crystallography was carried out to solve the structure of PmrA receiver domain. Electrophoretic mobility shift assay and Isothermal titration calorimetry were recruited to validate the interaction between the recombinant PmrA protein and …
METHODS: X-ray crystallography was carried out to solve the structure of PmrA receiver domain. Electrophoretic mobility shi …
Alfalfa MsbHLH115 confers tolerance to cadmium stress through activating the iron deficiency response in Arabidopsis thaliana.
Zhang M, Gao JY, Dong SC, Chang MH, Zhu JX, Guo DL, Guo CH, Bi YD. Zhang M, et al. Front Plant Sci. 2024 Feb 12;15:1358673. doi: 10.3389/fpls.2024.1358673. eCollection 2024. Front Plant Sci. 2024. PMID: 38410731 Free PMC article.
Further investigations revealed that MsbHLH115 up-regulated iron homeostasis regulation genes, ROS-related genes, and metal chelation and detoxification genes, contributing to attenuating Cd toxicity. Y1H, EMSA, and LUC assays confirmed the physical interaction between Msb …
Further investigations revealed that MsbHLH115 up-regulated iron homeostasis regulation genes, ROS-related genes, and metal chelation and de …
Fine-scale mapping of chromosome 9q22.33 identifies candidate causal variant in ovarian cancer.
Xing T, Zhao Y, Wang L, Geng W, Liu W, Zhou J, Huang C, Wang W, Chu X, Liu B, Chen K, Zheng H, Li L. Xing T, et al. PeerJ. 2024 Feb 14;12:e16918. doi: 10.7717/peerj.16918. eCollection 2024. PeerJ. 2024. PMID: 38371376 Free PMC article.
Expression quantitative trait locus (eQTL) analysis found that rs7027650 was significantly correlated with COL15A1 gene expression (P = 0.009). The Luciferase reporter gene assay confirmed that rs7027650 could interact with the promoter region of COL15A1, reducing its acti …
Expression quantitative trait locus (eQTL) analysis found that rs7027650 was significantly correlated with COL15A1 gene expression (P = 0.00 …
Trans-replicase helper activity of porcine circoviruses promotes the synergistic replication of torque teno virus.
Ssemadaali M, Islam MT, Fang W, Aboezz Z, Webb B, Ramamoorthy S. Ssemadaali M, et al. Front Microbiol. 2024 Jan 23;15:1326696. doi: 10.3389/fmicb.2024.1326696. eCollection 2024. Front Microbiol. 2024. PMID: 38322315 Free PMC article.
Therefore, the hypothesis that the PCV replicase (rep) protein has trans-replicase helper activity for TTSuV1 was examined. Based on EMSA and reporter gene assays, it was determined that the PCV1 rep directly interacted with the TTSuV1 UTR. ...
Therefore, the hypothesis that the PCV replicase (rep) protein has trans-replicase helper activity for TTSuV1 was examined. Based on EMSA …
Active oxygen generation induced by the glucose sensor TaHXK7-1A decreased the drought resistance of transgenic Arabidopsis and wheat (Triticum aestivum L.).
Tang P, Shan S, Wang R, Xu W, Yan N, Niu N, Zhang G, Gao X, Min D, Song Y. Tang P, et al. Plant Physiol Biochem. 2024 Feb;207:108410. doi: 10.1016/j.plaphy.2024.108410. Epub 2024 Jan 30. Plant Physiol Biochem. 2024. PMID: 38310725
.(-) and MDA in wheat leaves under drought stress, and the RBOHs was significantly down-regulated, which improved the drought resistance of wheat. The results of yeast one-hybrid, EMSA, and dual-luciferase assays showed that TabHLH148-5A bound to the E-box motif of the TaH …
.(-) and MDA in wheat leaves under drought stress, and the RBOHs was significantly down-regulated, which improved the drought resistance of …
Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks.
Lay MA, Thompson VF, Adelakun AD, Schwartz JC. Lay MA, et al. bioRxiv [Preprint]. 2024 Jan 21:2024.01.20.576463. doi: 10.1101/2024.01.20.576463. bioRxiv. 2024. PMID: 38293191 Free PMC article. Updated. Preprint.
In this study, we investigated the mechanism for EWSR1 to recognize an R-loop structure specifically. Using electrophoretic mobility shift assays (EMSA), we detected the high affinity binding of EWSR1 to substrates representing components found in R-lo …
In this study, we investigated the mechanism for EWSR1 to recognize an R-loop structure specifically. Using electrophoretic mobili …
BARX1 repressed FOXF1 expression and activated Wnt/β-catenin signaling pathway to drive lung adenocarcinoma.
Guan X, Liang J, Xiang Y, Li T, Zhong X. Guan X, et al. Int J Biol Macromol. 2024 Mar;261(Pt 2):129717. doi: 10.1016/j.ijbiomac.2024.129717. Epub 2024 Jan 28. Int J Biol Macromol. 2024. PMID: 38290639
CCK-8, colony formation, transwell, and wound healing assays examined proliferation, colony formation, invasion, and migration of LUAD cells, respectively. Electrophoretic mobility shift assay and chromatin immunoprecipitation assay examined the …
CCK-8, colony formation, transwell, and wound healing assays examined proliferation, colony formation, invasion, and migration of LUAD cells …
3,957 results