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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1990 1
1992 2
1993 1
1994 2
1995 2
1996 4
1997 2
1998 4
1999 2
2000 9
2001 5
2002 8
2003 9
2004 14
2005 12
2006 17
2007 15
2008 22
2009 22
2010 29
2011 40
2012 32
2013 53
2014 56
2015 80
2016 69
2017 77
2018 93
2019 83
2020 108
2021 109
2022 98
2023 92
2024 50

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1,080 results

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Page 1
Efficacy and safety of novel multifunctional M10 CAR-T cells in HIV-1-infected patients: a phase I, multicenter, single-arm, open-label study.
Mao Y, Liao Q, Zhu Y, Bi M, Zou J, Zheng N, Zhu L, Zhao C, Liu Q, Liu L, Chen J, Gu L, Liu Z, Pan X, Xue Y, Feng M, Ying T, Zhou P, Wu Z, Xiao J, Zhang R, Leng J, Sun Y, Zhang X, Xu J. Mao Y, et al. Cell Discov. 2024 May 14;10(1):49. doi: 10.1038/s41421-024-00658-z. Cell Discov. 2024. PMID: 38740803 Free PMC article.
Here, we report newly developed anti-HIV-1 CAR-T cells armed with endogenic broadly neutralizing antibodies (bNAbs) and the follicle-homing receptor CXCR5, termed M10 cells. M10 cells were designed to exercise three-fold biological functions, including broad cytotoxic effe …
Here, we report newly developed anti-HIV-1 CAR-T cells armed with endogenic broadly neutralizing antibodies (bNAbs) and the follicle-homi …
Early larval exposure to flumethrin induces long-term impacts on survival and memory behaviors of adult worker bees Apis mellifera.
Shi J, Liu C, Zhang Y, Wu X. Shi J, et al. Pestic Biochem Physiol. 2024 May;201:105909. doi: 10.1016/j.pestbp.2024.105909. Epub 2024 Apr 10. Pestic Biochem Physiol. 2024. PMID: 38685230
Furthermore, larval exposure at 1 mg/L flumethrin influenced the correct proboscis extension responses of 7-day-old worker bees and decreased homing rates of 20-day-old worker bees, suggesting that 1 mg/L flumethrin exposure at larval stage could affect memory-related beha …
Furthermore, larval exposure at 1 mg/L flumethrin influenced the correct proboscis extension responses of 7-day-old worker bees and decrease …
Bushen Huoxue recipe ameliorates ovarian function via promoting BMSCs proliferation and homing to ovaries in POI mice.
Huang Y, Hu R, Liu Z, Geng Y, Li F, Song Y, Ma W, Dong H, Xu L, Zhang M, Song K. Huang Y, et al. Phytomedicine. 2024 Apr 24;129:155630. doi: 10.1016/j.phymed.2024.155630. Online ahead of print. Phytomedicine. 2024. PMID: 38678952 Free article.
In addition, BHR promoted BMSCs proliferation, migration, and homing to the ovary, which was mediated by the SDF-1/CXCR4 and HGF/cMET signaling axis. Finally, the amelioration of ovarian reserve and ovarian function in CTX-induced POI mice by BHR may be related to its prom …
In addition, BHR promoted BMSCs proliferation, migration, and homing to the ovary, which was mediated by the SDF-1/CXCR4 and HGF/cMET …
MiRNA-148a-containing GMSC-derived EVs modulate Treg/Th17 balance via IKKB/NF-κB pathway and treat a rheumatoid arthritis model.
Chen J, Shi X, Deng Y, Dang J, Liu Y, Zhao J, Rongzhen L, Zeng D, Wu W, Xiong Y, Yuan J, Chen Y, Wang J, Lin W, Chen X, Huang W, Olsen N, Pan Y, Fu QL, Zheng SG. Chen J, et al. JCI Insight. 2024 Apr 23:e177841. doi: 10.1172/jci.insight.177841. Online ahead of print. JCI Insight. 2024. PMID: 38652539 Free article.
Through in vivo experiments using an experimental RA model, our results demonstrated that GMSC-EVs selectively homed to inflamed joints and recovered Treg and Th17 cells balance, resulting in the reduction of arthritis progression. ...
Through in vivo experiments using an experimental RA model, our results demonstrated that GMSC-EVs selectively homed to inflamed join …
Sulfated Polysaccharide-Based Nanocarrier Drives Microenvironment-Mediated Cerebral Neurovascular Remodeling for Ischemic Stroke Treatment.
Cao Y, Yu Y, Pan L, Han W, Zeng F, Wang J, Mei Q, Liu C. Cao Y, et al. Nano Lett. 2024 May 1;24(17):5214-5223. doi: 10.1021/acs.nanolett.4c00650. Epub 2024 Apr 22. Nano Lett. 2024. PMID: 38649327
The nanocarrier consisted of a sulfated chitosan (SCS) polymer core modified with a ROS-responsive boronic ester enveloped by a red blood cell membrane shell incorporating a stroke homing peptide. When encountering high levels of intracellular ROS in ischemic brain tissues …
The nanocarrier consisted of a sulfated chitosan (SCS) polymer core modified with a ROS-responsive boronic ester enveloped by a red blood ce …
Doxorubicin-based ENO1 targeted drug delivery strategy enhances therapeutic efficacy against colorectal cancer.
Liu J, Hu X, Yu G, Wang Q, Gu L, Shen J, Zhao Q, Sun H, Wang S, Guo Z, Zhao Y, Ma H. Liu J, et al. Biochem Pharmacol. 2024 Apr 17;224:116220. doi: 10.1016/j.bcp.2024.116220. Online ahead of print. Biochem Pharmacol. 2024. PMID: 38641307
Moreover, DOX-P exhibited acid-responsive capabilities, enabling precise release at the tumor site under the guidance of the homing peptide and alleviating DOX-induced cardiotoxicity. An efficacy experiment confirmed that, the targeting ability of DOX-P toward ENO1 demonst …
Moreover, DOX-P exhibited acid-responsive capabilities, enabling precise release at the tumor site under the guidance of the homing p …
CSF1R blockade slows progression of cerebral hemorrhage by reducing microglial proliferation and increasing infiltration of CD8 + CD122+ T cells into the brain.
Cheng F, Wang C, Yan B, Yin Z, Liu Y, Zhang L, Li M, Liao P, Gao H, Jia Z, Li D, Liu Q, Lei P. Cheng F, et al. Int Immunopharmacol. 2024 May 30;133:112071. doi: 10.1016/j.intimp.2024.112071. Epub 2024 Apr 17. Int Immunopharmacol. 2024. PMID: 38636374
This intervention was associated with a decrease in pro-inflammatory factors in microglia and an increased infiltration of peripheral regulatory CD8 + CD122+ T cells into the injured brain tissue. The CXCR3/CXCL10 axis is the mechanism of brain homing of regulatory CD8 + C …
This intervention was associated with a decrease in pro-inflammatory factors in microglia and an increased infiltration of peripheral regula …
Small Extracellular Vesicles Promote Stiffness-mediated Metastasis.
Sneider A, Liu Y, Starich B, Du W, Nair PR, Marar C, Faqih N, Ciotti GE, Kim JH, Krishnan S, Ibrahim S, Igboko M, Locke A, Lewis DM, Hong H, Karl MN, Vij R, Russo GC, Gómez-de-Mariscal E, Habibi M, Muñoz-Barrutia A, Gu L, Eisinger-Mathason TSK, Wirtz D. Sneider A, et al. Cancer Res Commun. 2024 May 9;4(5):1240-1252. doi: 10.1158/2767-9764.CRC-23-0431. Cancer Res Commun. 2024. PMID: 38630893 Free PMC article.
Primary patient breast tissue released by cancer cells on matrices that model human breast tumors (25 kPa; stiff EVs) feature increased adhesion molecule presentation (ITGalpha2beta1, ITGalpha6beta4, ITGalpha6beta1, CD44) compared with EVs from softer normal tissue (0.5 kPa; soft …
Primary patient breast tissue released by cancer cells on matrices that model human breast tumors (25 kPa; stiff EVs) feature increased adhe …
Engineering biomimetic nanosystem targeting multiple tumor radioresistance hallmarks for enhanced radiotherapy.
Wang S, Cao H, Zhao CC, Wang Q, Wang D, Liu J, Yang L, Liu J. Wang S, et al. Sci China Life Sci. 2024 Apr 7. doi: 10.1007/s11427-023-2528-5. Online ahead of print. Sci China Life Sci. 2024. PMID: 38602587
After administration, M@HHPt actively targeted and smoothly accumulated in tumor cells by virtue of its innate homing abilities to realize efficient co-delivery of O(2) and Pt(IV). ...
After administration, M@HHPt actively targeted and smoothly accumulated in tumor cells by virtue of its innate homing abilities to re …
1,080 results