Relaxin treatment reduces angiotensin II-induced vasoconstriction in pregnancy and protects against endothelial dysfunction†.
Marshall SA, Leo CH, Girling JE, Tare M, Beard S, Hannan NJ, Parry LJ.
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PMID: 28379296
In the second study, mesenteric arteries were incubated ex vivo for 24 h at 37C in TCM, which contained high levels of soluble Flt-1 (>20 ng/ml) and soluble Eng (>1 ng/ml). TCM incubation caused significant reduction in endothelium-dependent relaxation and increased …
In the second study, mesenteric arteries were incubated ex vivo for 24 h at 37C in TCM, which contained high levels of soluble Flt-1 (>20 …