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Inducing and exploiting vulnerabilities for the treatment of liver cancer.
Nature. 2019 Oct;574(7777):268-272. doi: 10.1038/s41586-019-1607-3. Epub 2019 Oct 2.
Nature. 2019.
PMID: 31578521
Free PMC article.
CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma.
Wang C, Wang H, Lieftink C, du Chatinier A, Gao D, Jin G, Jin H, Beijersbergen RL, Qin W, Bernards R.
Wang C, et al. Among authors: du chatinier a.
Gut. 2020 Apr;69(4):727-736. doi: 10.1136/gutjnl-2019-318506. Epub 2019 Sep 13.
Gut. 2020.
PMID: 31519701
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AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma.
Metselaar DS, du Chatinier A, Meel MH, Ter Huizen G, Waranecki P, Goulding JR, Bugiani M, Koster J, Kaspers GJL, Hulleman E.
Metselaar DS, et al. Among authors: du chatinier a.
iScience. 2022 May 13;25(6):104398. doi: 10.1016/j.isci.2022.104398. eCollection 2022 Jun 17.
iScience. 2022.
PMID: 35637734
Free PMC article.
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Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma.
du Chatinier A, Meel MH, Das AI, Metselaar DS, Waranecki P, Bugiani M, Breur M, Simonds EF, Lu ED, Weiss WA, Garcia Vallejo JJ, Hoving EW, Phoenix TN, Hulleman E.
du Chatinier A, et al.
Neurooncol Adv. 2022 May 24;4(1):vdac079. doi: 10.1093/noajnl/vdac079. eCollection 2022 Jan-Dec.
Neurooncol Adv. 2022.
PMID: 35733514
Free PMC article.
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Radiosensitization in Pediatric High-Grade Glioma: Targets, Resistance and Developments.
Metselaar DS, du Chatinier A, Stuiver I, Kaspers GJL, Hulleman E.
Metselaar DS, et al. Among authors: du chatinier a.
Front Oncol. 2021 Apr 1;11:662209. doi: 10.3389/fonc.2021.662209. eCollection 2021.
Front Oncol. 2021.
PMID: 33869066
Free PMC article.
Review.
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Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1.
Cornel AM, van der Sman L, van Dinter JT, Arrabito M, Dunnebach E, van Hoesel M, Kluiver TA, Lopes AP, Dautzenberg NMM, Dekker L, van Rijn JM, van den Beemt DAMH, Buhl JL, du Chatinier A, Barneh F, Lu Y, Lo Nigro L, Krippner-Heidenreich A, Sebestyén Z, Kuball J, Hulleman E, Drost J, van Heesch S, Heidenreich OT, Peng WC, Nierkens S.
Cornel AM, et al. Among authors: du chatinier a.
J Immunother Cancer. 2024 Mar 21;12(3):e007538. doi: 10.1136/jitc-2023-007538.
J Immunother Cancer. 2024.
PMID: 38519054
Free PMC article.
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Microglia in pediatric brain tumors: The missing link to successful immunotherapy.
du Chatinier A, Velilla IQ, Meel MH, Hoving EW, Hulleman E, Metselaar DS.
du Chatinier A, et al.
Cell Rep Med. 2023 Nov 21;4(11):101246. doi: 10.1016/j.xcrm.2023.101246. Epub 2023 Nov 3.
Cell Rep Med. 2023.
PMID: 37924816
Free PMC article.
Review.
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Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.
Mulero-Sánchez A, Ramirez CFA, du Chatinier A, Wang H, Koomen SJI, Song JY, de Groot MHP, Lieftink C, Bosma A, Burylo A, van Tellingen O, Beijersbergen RL, Wang C, Akkari L, Bernards R, Mainardi S.
Mulero-Sánchez A, et al. Among authors: du chatinier a.
Mol Oncol. 2023 Jun;17(6):964-980. doi: 10.1002/1878-0261.13377. Epub 2023 Feb 9.
Mol Oncol. 2023.
PMID: 36650715
Free PMC article.
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