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Tumor ablation plus co-administration of CpG and saponin adjuvants affects IL-1 production and multifunctional T cell numbers in tumor draining lymph nodes.
Raaijmakers TK, van den Bijgaart RJE, den Brok MH, Wassink M, de Graaf A, Wagenaars JA, Nierkens S, Ansems M, Scheffer GJ, Adema GJ. Raaijmakers TK, et al. Among authors: den brok mh. J Immunother Cancer. 2020 May;8(1):e000649. doi: 10.1136/jitc-2020-000649. J Immunother Cancer. 2020. PMID: 32461350 Free PMC article.
Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells.
Nierkens S, den Brok MH, Garcia Z, Togher S, Wagenaars J, Wassink M, Boon L, Ruers TJ, Figdor CG, Schoenberger SP, Adema GJ, Janssen EM. Nierkens S, et al. Among authors: den brok mh. Cancer Res. 2011 Oct 15;71(20):6428-37. doi: 10.1158/0008-5472.CAN-11-2154. Epub 2011 Jul 25. Cancer Res. 2011. PMID: 21788345 Free PMC article.
Sweet escape: sialic acids in tumor immune evasion.
Büll C, den Brok MH, Adema GJ. Büll C, et al. Among authors: den brok mh. Biochim Biophys Acta. 2014 Aug;1846(1):238-46. doi: 10.1016/j.bbcan.2014.07.005. Epub 2014 Jul 12. Biochim Biophys Acta. 2014. PMID: 25026312 Review.
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