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Human heart-forming organoids recapitulate early heart and foregut development.
Drakhlis L, Biswanath S, Farr CM, Lupanow V, Teske J, Ritzenhoff K, Franke A, Manstein F, Bolesani E, Kempf H, Liebscher S, Schenke-Layland K, Hegermann J, Nolte L, Meyer H, de la Roche J, Thiemann S, Wahl-Schott C, Martin U, Zweigerdt R. Drakhlis L, et al. Among authors: de la roche j. Nat Biotechnol. 2021 Jun;39(6):737-746. doi: 10.1038/s41587-021-00815-9. Epub 2021 Feb 8. Nat Biotechnol. 2021. PMID: 33558697 Free PMC article.
Publisher Correction: Human heart-forming organoids recapitulate early heart and foregut development.
Drakhlis L, Biswanath S, Farr CM, Lupanow V, Teske J, Ritzenhoff K, Franke A, Manstein F, Bolesani E, Kempf H, Liebscher S, Schenke-Layland K, Hegermann J, Nolte L, Meyer H, de la Roche J, Thiemann S, Wahl-Schott C, Martin U, Zweigerdt R. Drakhlis L, et al. Among authors: de la roche j. Nat Biotechnol. 2021 Jun;39(6):775. doi: 10.1038/s41587-021-00960-1. Nat Biotechnol. 2021. PMID: 34017142 Free PMC article. No abstract available.
Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels.
de la Roche J, Angsutararux P, Kempf H, Janan M, Bolesani E, Thiemann S, Wojciechowski D, Coffee M, Franke A, Schwanke K, Leffler A, Luanpitpong S, Issaragrisil S, Fischer M, Zweigerdt R. de la Roche J, et al. Sci Rep. 2019 Aug 1;9(1):11173. doi: 10.1038/s41598-019-47632-4. Sci Rep. 2019. PMID: 31371804 Free PMC article.
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture.
Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N, Osten F, de la Roche J, Polten F, Christoph Wollert K, Kraft T, Fischer M, Martin U, Gruh I, Kempf H, Zweigerdt R. Halloin C, et al. Among authors: de la roche j. Stem Cell Reports. 2019 Aug 13;13(2):366-379. doi: 10.1016/j.stemcr.2019.06.004. Epub 2019 Jul 25. Stem Cell Reports. 2019. PMID: 31353227 Free PMC article.
EBIO Does Not Induce Cardiomyogenesis in Human Pluripotent Stem Cells but Modulates Cardiac Subtype Enrichment by Lineage-Selective Survival.
Jara-Avaca M, Kempf H, Rückert M, Robles-Diaz D, Franke A, de la Roche J, Fischer M, Malan D, Sasse P, Solodenko W, Dräger G, Kirschning A, Martin U, Zweigerdt R. Jara-Avaca M, et al. Among authors: de la roche j. Stem Cell Reports. 2017 Feb 14;8(2):305-317. doi: 10.1016/j.stemcr.2016.12.012. Epub 2017 Jan 12. Stem Cell Reports. 2017. PMID: 28089668 Free PMC article.
Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform.
Weber N, Kowalski K, Holler T, Radocaj A, Fischer M, Thiemann S, de la Roche J, Schwanke K, Piep B, Peschel N, Krumm U, Lingk A, Wendland M, Greten S, Schmitto JD, Ismail I, Warnecke G, Zywietz U, Chichkov B, Meißner J, Haverich A, Martin U, Brenner B, Zweigerdt R, Kraft T. Weber N, et al. Among authors: de la roche j. Stem Cell Reports. 2020 May 12;14(5):788-802. doi: 10.1016/j.stemcr.2020.03.015. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302556 Free PMC article.
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture.
Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N, Osten F, de la Roche J, Polten F, Christoph Wollert K, Kraft T, Fischer M, Martin U, Gruh I, Kempf H, Zweigerdt R. Halloin C, et al. Among authors: de la roche j. Stem Cell Reports. 2019 Oct 8;13(4):775. doi: 10.1016/j.stemcr.2019.09.001. Stem Cell Reports. 2019. PMID: 31597111 Free PMC article. No abstract available.
Preclinical development of a miR-132 inhibitor for heart failure treatment.
Foinquinos A, Batkai S, Genschel C, Viereck J, Rump S, Gyöngyösi M, Traxler D, Riesenhuber M, Spannbauer A, Lukovic D, Weber N, Zlabinger K, Hašimbegović E, Winkler J, Fiedler J, Dangwal S, Fischer M, de la Roche J, Wojciechowski D, Kraft T, Garamvölgyi R, Neitzel S, Chatterjee S, Yin X, Bär C, Mayr M, Xiao K, Thum T. Foinquinos A, et al. Among authors: de la roche j. Nat Commun. 2020 Jan 31;11(1):633. doi: 10.1038/s41467-020-14349-2. Nat Commun. 2020. PMID: 32005803 Free PMC article.
36 results