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Page 1
GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways.
Guerenne L, Beurlet S, Said M, Gorombei P, Le Pogam C, Guidez F, de la Grange P, Omidvar N, Vanneaux V, Mills K, Mufti GJ, Sarda-Mantel L, Noguera ME, Pla M, Fenaux P, Padua RA, Chomienne C, Krief P. Guerenne L, et al. Among authors: de la grange p. J Hematol Oncol. 2016 Jan 27;9:5. doi: 10.1186/s13045-016-0235-8. J Hematol Oncol. 2016. PMID: 26817437 Free PMC article.
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
Gorombei P, Guidez F, Ganesan S, Chiquet M, Pellagatti A, Goursaud L, Tekin N, Beurlet S, Patel S, Guerenne L, Le Pogam C, Setterblad N, de la Grange P, LeBoeuf C, Janin A, Noguera ME, Sarda-Mantel L, Merlet P, Boultwood J, Konopleva M, Andreeff M, West R, Pla M, Adès L, Fenaux P, Krief P, Chomienne C, Omidvar N, Padua RA. Gorombei P, et al. Among authors: de la grange p. Int J Mol Sci. 2021 Sep 30;22(19):10658. doi: 10.3390/ijms221910658. Int J Mol Sci. 2021. PMID: 34638998 Free PMC article.
BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.
Beurlet S, Omidvar N, Gorombei P, Krief P, Le Pogam C, Setterblad N, de la Grange P, Leboeuf C, Janin A, Noguera ME, Hervatin F, Sarda-Mantel L, Konopleva M, Andreeff M, Tu AW, Fan AC, Felsher DW, Whetton A, Pla M, West R, Fenaux P, Chomienne C, Padua RA. Beurlet S, et al. Among authors: de la grange p. Blood. 2013 Oct 17;122(16):2864-76. doi: 10.1182/blood-2012-07-445635. Epub 2013 Aug 13. Blood. 2013. PMID: 23943652 Free PMC article.
Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.
Domenech C, Maillard L, Rousseau A, Guidez F, Petit L, Pla M, Clay D, Guimiot F, Sanfilippo S, Jacques S, de la Grange P, Robil N, Soulier J, Souyri M. Domenech C, et al. Among authors: de la grange p. Stem Cell Reports. 2018 Nov 13;11(5):1075-1091. doi: 10.1016/j.stemcr.2018.10.001. Epub 2018 Oct 25. Stem Cell Reports. 2018. PMID: 30449320 Free PMC article.
CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.
Astori A, Fredly H, Aloysius TA, Bullinger L, Mansat-De Mas V, de la Grange P, Delhommeau F, Hagen KM, Récher C, Dusanter-Fourt I, Knappskog S, Lillehaug JR, Pendino F, Bruserud Ø. Astori A, et al. Among authors: de la grange p. Oncotarget. 2013 Sep;4(9):1438-48. doi: 10.18632/oncotarget.1195. Oncotarget. 2013. PMID: 23988457 Free PMC article.
hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.
Chapat C, Kolytcheff C, Le Romancer M, Auboeuf D, De La Grange P, Chettab K, Sentis S, Corbo L. Chapat C, et al. Among authors: de la grange p. EMBO J. 2013 Mar 6;32(5):688-700. doi: 10.1038/emboj.2013.11. Epub 2013 Feb 5. EMBO J. 2013. PMID: 23386060 Free PMC article.
Splicing factor and exon profiling across human tissues.
de la Grange P, Gratadou L, Delord M, Dutertre M, Auboeuf D. de la Grange P, et al. Nucleic Acids Res. 2010 May;38(9):2825-38. doi: 10.1093/nar/gkq008. Epub 2010 Jan 27. Nucleic Acids Res. 2010. PMID: 20110256 Free PMC article.
Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization.
Vallerand D, Massonnet G, Kébir F, Gentien D, Maciorowski Z, De la Grange P, Sigal-Zafrani B, Richardson M, Humbert S, Thuleau A, Assayag F, de Plater L, Nicolas A, Scholl S, Marangoni E, Weigand S, Roman-Roman S, Savina A, Decaudin D. Vallerand D, et al. Among authors: de la grange p, de plater l. PLoS One. 2016 Jul 7;11(7):e0157670. doi: 10.1371/journal.pone.0157670. eCollection 2016. PLoS One. 2016. PMID: 27388901 Free PMC article.
101 results