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Crystal structure of the α1B-adrenergic receptor reveals molecular determinants of selective ligand recognition.
Deluigi M, Morstein L, Schuster M, Klenk C, Merklinger L, Cridge RR, de Zhang LA, Klipp A, Vacca S, Vaid TM, Mittl PRE, Egloff P, Eberle SA, Zerbe O, Chalmers DK, Scott DJ, Plückthun A. Deluigi M, et al. Among authors: de zhang la. Nat Commun. 2022 Jan 19;13(1):382. doi: 10.1038/s41467-021-27911-3. Nat Commun. 2022. PMID: 35046410 Free PMC article.
Unravelling the mechanism of neurotensin recognition by neurotensin receptor 1.
Asadollahi K, Rajput S, de Zhang LA, Ang CS, Nie S, Williamson NA, Griffin MDW, Bathgate RAD, Scott DJ, Weikl TR, Jameson GNL, Gooley PR. Asadollahi K, et al. Among authors: de zhang la. Nat Commun. 2023 Dec 9;14(1):8155. doi: 10.1038/s41467-023-44010-7. Nat Commun. 2023. PMID: 38071229 Free PMC article.
Identification of a Novel Subtype-Selective α1B-Adrenoceptor Antagonist.
Abdul-Ridha A, de Zhang LA, Betrie AH, Deluigi M, Vaid TM, Whitehead A, Zhang Y, Davis B, Harris R, Simmonite H, Hubbard RE, Gooley PR, Plückthun A, Bathgate RAD, Chalmers DK, Scott DJ. Abdul-Ridha A, et al. Among authors: de zhang la. ACS Chem Neurosci. 2024 Feb 7;15(3):671-684. doi: 10.1021/acschemneuro.3c00767. Epub 2024 Jan 18. ACS Chem Neurosci. 2024. PMID: 38238043