de Witte P - Search Results

1

Current insights in the complexities underlying drug-induced cholestasis.

Deferm N, De Vocht T, Qi B, Van Brantegem P, Gijbels E, Vinken M, de Witte P, Bouillon T, Annaert P. Deferm N, et al. Among authors: de witte p, de vocht t. Crit Rev Toxicol. 2019 Jul;49(6):520-548. doi: 10.1080/10408444.2019.1635081. Epub 2019 Oct 7. Crit Rev Toxicol. 2019. PMID: 31589080 Review.

2

Structure-based identification of OATP1B1/3 inhibitors.

De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP. De Bruyn T, et al. Among authors: de witte p. Mol Pharmacol. 2013 Jun;83(6):1257-67. doi: 10.1124/mol.112.084152. Epub 2013 Apr 9. Mol Pharmacol. 2013. PMID: 23571415

3

Cell Imaging Counting as a Novel Ex Vivo Approach for Investigating Drug-Induced Hepatotoxicity in Zebrafish Larvae.

Nguyen XB, Kislyuk S, Pham DH, Kecskés A, Maes J, Cabooter D, Annaert P, De Witte P, Ny A. Nguyen XB, et al. Among authors: de witte p. Int J Mol Sci. 2017 Feb 8;18(2):356. doi: 10.3390/ijms18020356. Int J Mol Sci. 2017. PMID: 28208716 Free PMC article.

4

Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos.

Giusti A, Nguyen XB, Kislyuk S, Mignot M, Ranieri C, Nicolaï J, Oorts M, Wu X, Annaert P, De Croze N, Léonard M, Ny A, Cabooter D, de Witte P. Giusti A, et al. Among authors: de witte p, de croze n. Int J Mol Sci. 2019 Apr 6;20(7):1712. doi: 10.3390/ijms20071712. Int J Mol Sci. 2019. PMID: 30959884 Free PMC article.

5

Detection of Drug-Induced Cholestasis Potential in Sandwich-Cultured Human Hepatocytes.

Deferm N, Richert L, Van Brantegem P, De Vocht T, Qi B, de Witte P, Bouillon T, Annaert P. Deferm N, et al. Among authors: de witte p, de vocht t. Methods Mol Biol. 2019;1981:335-350. doi: 10.1007/978-1-4939-9420-5_22. Methods Mol Biol. 2019. PMID: 31016665

6

Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration.

Guarin M, Faelens R, Giusti A, De Croze N, Léonard M, Cabooter D, Annaert P, de Witte P, Ny A. Guarin M, et al. Among authors: de witte p, de croze n. Sci Rep. 2021 Jun 9;11(1):12229. doi: 10.1038/s41598-021-91612-6. Sci Rep. 2021. PMID: 34108572 Free PMC article.

7

Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis.

Guarin M, Ny A, De Croze N, Maes J, Léonard M, Annaert P, de Witte PAM. Guarin M, et al. Among authors: de croze n, de witte pam. Pharmaceuticals (Basel). 2021 Jun 16;14(6):576. doi: 10.3390/ph14060576. Pharmaceuticals (Basel). 2021. PMID: 34208572 Free PMC article.

8

Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?

Mesens N, Crawford AD, Menke A, Hung PD, Van Goethem F, Nuyts R, Hansen E, Wolterbeek A, Van Gompel J, De Witte P, Esguerra CV. Mesens N, et al. Among authors: de witte p. J Appl Toxicol. 2015 Sep;35(9):1017-29. doi: 10.1002/jat.3091. Epub 2015 Feb 6. J Appl Toxicol. 2015. PMID: 25663337

9

Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid.

Wang X, Giusti A, Ny A, de Witte PA. Wang X, et al. Toxins (Basel). 2020 Mar 30;12(4):217. doi: 10.3390/toxins12040217. Toxins (Basel). 2020. PMID: 32235450 Free PMC article.

10

Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs.

Afrikanova T, Serruys AS, Buenafe OE, Clinckers R, Smolders I, de Witte PA, Crawford AD, Esguerra CV. Afrikanova T, et al. PLoS One. 2013;8(1):e54166. doi: 10.1371/journal.pone.0054166. Epub 2013 Jan 14. PLoS One. 2013. PMID: 23342097 Free PMC article.

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