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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age-dependent differences in absorption.
Streekstra EJ, Kiss M, van den Heuvel J, Nicolaï J, van den Broek P, Botden SMBI, Stommel MWJ, van Rijssel L, Ungell AL, van de Steeg E, Russel FGM, de Wildt SN. Streekstra EJ, et al. Among authors: de wildt sn. Clin Transl Sci. 2022 Oct;15(10):2392-2402. doi: 10.1111/cts.13368. Epub 2022 Aug 12. Clin Transl Sci. 2022. PMID: 35962572 Free PMC article.
Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium.
Evers R, Piquette-Miller M, Polli JW, Russel FGM, Sprowl JA, Tohyama K, Ware JA, de Wildt SN, Xie W, Brouwer KLR; International Transporter Consortium. Evers R, et al. Among authors: de wildt sn. Clin Pharmacol Ther. 2018 Nov;104(5):900-915. doi: 10.1002/cpt.1115. Epub 2018 Jul 12. Clin Pharmacol Ther. 2018. PMID: 29756222 Free PMC article.
Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants.
van Groen BD, van de Steeg E, Mooij MG, van Lipzig MMH, de Koning BAE, Verdijk RM, Wortelboer HM, Gaedigk R, Bi C, Leeder JS, van Schaik RHN, van Rosmalen J, Tibboel D, Vaes WH, de Wildt SN. van Groen BD, et al. Among authors: de koning bae, de wildt sn. Eur J Pharm Sci. 2018 Nov 1;124:217-227. doi: 10.1016/j.ejps.2018.08.042. Epub 2018 Aug 30. Eur J Pharm Sci. 2018. PMID: 30171984 Free article.
Involve Children and Parents in Clinical Studies.
Vermeulen E, Karsenberg K, van der Lee JH, de Wildt SN. Vermeulen E, et al. Among authors: de wildt sn. Clin Transl Sci. 2020 Jan;13(1):11-13. doi: 10.1111/cts.12696. Epub 2019 Oct 24. Clin Transl Sci. 2020. PMID: 31647179 Free PMC article. No abstract available.
244 results