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Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways.
Schimmel J, Muñoz-Subirana N, Kool H, van Schendel R, van der Vlies S, Kamp JA, de Vrij FMS, Kushner SA, Smith GCM, Boulton SJ, Tijsterman M. Schimmel J, et al. Among authors: de vrij fms. Cell Rep. 2023 Feb 28;42(2):112019. doi: 10.1016/j.celrep.2023.112019. Epub 2023 Jan 25. Cell Rep. 2023. PMID: 36701230 Free article.
Epigenetic characterization of the FMR1 promoter in induced pluripotent stem cells from human fibroblasts carrying an unmethylated full mutation.
de Esch CE, Ghazvini M, Loos F, Schelling-Kazaryan N, Widagdo W, Munshi ST, van der Wal E, Douben H, Gunhanlar N, Kushner SA, Pijnappel WW, de Vrij FM, Geijsen N, Gribnau J, Willemsen R. de Esch CE, et al. Stem Cell Reports. 2014 Oct 14;3(4):548-55. doi: 10.1016/j.stemcr.2014.07.013. Epub 2014 Sep 11. Stem Cell Reports. 2014. PMID: 25358783 Free PMC article.
A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells.
Gunhanlar N, Shpak G, van der Kroeg M, Gouty-Colomer LA, Munshi ST, Lendemeijer B, Ghazvini M, Dupont C, Hoogendijk WJG, Gribnau J, de Vrij FMS, Kushner SA. Gunhanlar N, et al. Among authors: de vrij fms. Mol Psychiatry. 2018 May;23(5):1336-1344. doi: 10.1038/mp.2017.56. Epub 2017 Apr 18. Mol Psychiatry. 2018. PMID: 28416807 Free PMC article.
SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells.
García-León JA, Kumar M, Boon R, Chau D, One J, Wolfs E, Eggermont K, Berckmans P, Gunhanlar N, de Vrij F, Lendemeijer B, Pavie B, Corthout N, Kushner SA, Dávila JC, Lambrichts I, Hu WS, Verfaillie CM. García-León JA, et al. Stem Cell Reports. 2018 Feb 13;10(2):655-672. doi: 10.1016/j.stemcr.2017.12.014. Epub 2018 Jan 11. Stem Cell Reports. 2018. PMID: 29337119 Free PMC article.
A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease.
Ghanbari M, Munshi ST, Ma B, Lendemeijer B, Bansal S, Adams HH, Wang W, Goth K, Slump DE, van den Hout MCGN, van IJcken WFJ, Bellusci S, Pan Q, Erkeland SJ, de Vrij FMS, Kushner SA, Ikram MA. Ghanbari M, et al. Among authors: de vrij fms. Hum Mutat. 2019 Nov;40(11):2131-2145. doi: 10.1002/humu.23872. Epub 2019 Aug 7. Hum Mutat. 2019. PMID: 31322790
The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2.
Bauer L, Laksono BM, de Vrij FMS, Kushner SA, Harschnitz O, van Riel D. Bauer L, et al. Among authors: de vrij fms. Trends Neurosci. 2022 May;45(5):358-368. doi: 10.1016/j.tins.2022.02.006. Epub 2022 Mar 3. Trends Neurosci. 2022. PMID: 35279295 Free PMC article. Review.
38 results