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Cross-reactivity of mouse IgG subclasses to human Fc gamma receptors: Antibody deglycosylation only eliminates IgG2b binding.
Temming AR, Bentlage AEH, de Taeye SW, Bosman GP, Lissenberg-Thunnissen SN, Derksen NIL, Brasser G, Mok JY, van Esch WJE, Howie HL, Zimring JC, Vidarsson G. Temming AR, et al. Among authors: de taeye sw. Mol Immunol. 2020 Nov;127:79-86. doi: 10.1016/j.molimm.2020.08.015. Epub 2020 Sep 15. Mol Immunol. 2020. PMID: 32947169 Free article.
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge.
Stapleton NM, Brinkhaus M, Armour KL, Bentlage AEH, de Taeye SW, Temming AR, Mok JY, Brasser G, Maas M, van Esch WJE, Clark MR, Williamson LM, van der Schoot CE, Vidarsson G. Stapleton NM, et al. Among authors: de taeye sw. Sci Rep. 2019 May 14;9(1):7363. doi: 10.1038/s41598-019-40731-2. Sci Rep. 2019. PMID: 31089170 Free PMC article.
The Ligands for Human IgG and Their Effector Functions.
de Taeye SW, Rispens T, Vidarsson G. de Taeye SW, et al. Antibodies (Basel). 2019 Apr 25;8(2):30. doi: 10.3390/antib8020030. Antibodies (Basel). 2019. PMID: 31544836 Free PMC article. Review.
Functional Attributes of Antibodies, Effector Cells, and Target Cells Affecting NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity.
Temming AR, de Taeye SW, de Graaf EL, de Neef LA, Dekkers G, Bruggeman CW, Koers J, Ligthart P, Nagelkerke SQ, Zimring JC, Kuijpers TW, Wuhrer M, Rispens T, Vidarsson G. Temming AR, et al. Among authors: de graaf el, de neef la, de taeye sw. J Immunol. 2019 Dec 15;203(12):3126-3135. doi: 10.4049/jimmunol.1900985. Epub 2019 Nov 20. J Immunol. 2019. PMID: 31748349
FcγR Binding and ADCC Activity of Human IgG Allotypes.
de Taeye SW, Bentlage AEH, Mebius MM, Meesters JI, Lissenberg-Thunnissen S, Falck D, Sénard T, Salehi N, Wuhrer M, Schuurman J, Labrijn AF, Rispens T, Vidarsson G. de Taeye SW, et al. Front Immunol. 2020 May 6;11:740. doi: 10.3389/fimmu.2020.00740. eCollection 2020. Front Immunol. 2020. PMID: 32435243 Free PMC article.
MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation.
Sénard T, Gargano AFG, Falck D, de Taeye SW, Rispens T, Vidarsson G, Wuhrer M, Somsen GW, Domínguez-Vega E. Sénard T, et al. Among authors: de taeye sw. Front Immunol. 2020 Aug 21;11:2049. doi: 10.3389/fimmu.2020.02049. eCollection 2020. Front Immunol. 2020. PMID: 32973813 Free PMC article.
Glycine 236 in the Lower Hinge Region of Human IgG1 Differentiates FcγR from Complement Effector Function.
Brinkhaus M, Douwes RGJ, Bentlage AEH, Temming AR, de Taeye SW, Tammes Buirs M, Gerritsen J, Mok JY, Brasser G, Ligthart PC, van Esch WJE, Verheesen P, de Haard H, Rispens T, Vidarsson G. Brinkhaus M, et al. Among authors: de taeye sw, de haard h. J Immunol. 2020 Dec 15;205(12):3456-3467. doi: 10.4049/jimmunol.2000961. Epub 2020 Nov 13. J Immunol. 2020. PMID: 33188070
IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming.
Hoepel W, Allahverdiyeva S, Harbiye H, de Taeye SW, van der Ham AJ, de Boer L, Zaat SAJ, van Weeghel M, Baeten DLP, Houtkooper RH, Everts B, Vidarsson G, den Dunnen J. Hoepel W, et al. Among authors: de boer l, de taeye sw. J Immunol. 2020 Dec 15;205(12):3400-3407. doi: 10.4049/jimmunol.2000263. Epub 2020 Nov 13. J Immunol. 2020. PMID: 33188071
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.
Larsen MD, de Graaf EL, Sonneveld ME, Plomp HR, Nouta J, Hoepel W, Chen HJ, Linty F, Visser R, Brinkhaus M, Šuštić T, de Taeye SW, Bentlage AEH, Toivonen S, Koeleman CAM, Sainio S, Kootstra NA, Brouwer PJM, Geyer CE, Derksen NIL, Wolbink G, de Winther M, Sanders RW, van Gils MJ, de Bruin S, Vlaar APJ; Amsterdam UMC COVID-19; biobank study group; Rispens T, den Dunnen J, Zaaijer HL, Wuhrer M, Ellen van der Schoot C, Vidarsson G. Larsen MD, et al. Among authors: de graaf el, de winther m, de taeye sw, de bruin s. Science. 2021 Feb 26;371(6532):eabc8378. doi: 10.1126/science.abc8378. Epub 2020 Dec 23. Science. 2021. PMID: 33361116 Free PMC article.
52 results