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Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer.
Paffenholz SV, Salvagno C, Ho YJ, Limjoco M, Baslan T, Tian S, Kulick A, de Stanchina E, Wilkinson JE, Barriga FM, Zamarin D, Cubillos-Ruiz JR, Leibold J, Lowe SW. Paffenholz SV, et al. Among authors: de stanchina e. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2117754119. doi: 10.1073/pnas.2117754119. Proc Natl Acad Sci U S A. 2022. PMID: 35082152 Free PMC article.
Oncogenic ras and p53 cooperate to induce cellular senescence.
Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW. Ferbeyre G, et al. Among authors: de stanchina e. Mol Cell Biol. 2002 May;22(10):3497-508. doi: 10.1128/MCB.22.10.3497-3508.2002. Mol Cell Biol. 2002. PMID: 11971980 Free PMC article.
Tumour suppression: something for nothing?
de Stanchina E, Lowe SW. de Stanchina E, et al. Nat Cell Biol. 2002 Dec;4(12):E275-6. doi: 10.1038/ncb1202-e275. Nat Cell Biol. 2002. PMID: 12461528 No abstract available.
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. Wendel HG, et al. Among authors: de stanchina e. Nature. 2004 Mar 18;428(6980):332-7. doi: 10.1038/nature02369. Nature. 2004. PMID: 15029198 Free article.
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition.
Wendel HG, de Stanchina E, Cepero E, Ray S, Emig M, Fridman JS, Veach DR, Bornmann WG, Clarkson B, McCombie WR, Kogan SC, Hochhaus A, Lowe SW. Wendel HG, et al. Among authors: de stanchina e. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7444-9. doi: 10.1073/pnas.0602402103. Epub 2006 May 1. Proc Natl Acad Sci U S A. 2006. PMID: 16651519 Free PMC article.
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.
Caldas-Lopes E, Cerchietti L, Ahn JH, Clement CC, Robles AI, Rodina A, Moulick K, Taldone T, Gozman A, Guo Y, Wu N, de Stanchina E, White J, Gross SS, Ma Y, Varticovski L, Melnick A, Chiosis G. Caldas-Lopes E, et al. Among authors: de stanchina e. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8368-73. doi: 10.1073/pnas.0903392106. Epub 2009 May 5. Proc Natl Acad Sci U S A. 2009. PMID: 19416831 Free PMC article.
Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor.
Bosbach B, Deshpande S, Rossi F, Shieh JH, Sommer G, de Stanchina E, Veach DR, Scandura JM, Manova-Todorova K, Moore MA, Antonescu CR, Besmer P. Bosbach B, et al. Among authors: de stanchina e. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):E2276-83. doi: 10.1073/pnas.1115240109. Epub 2012 May 31. Proc Natl Acad Sci U S A. 2012. PMID: 22652566 Free PMC article.
243 results