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Structure-activity relationships of novel N-imidazoylpiperazines with potent anti-Trypanosoma cruzi activity.
Espinoza-Chávez RM, Oliveira Rezende Júnior C, de Souza ML, Pauli I, Valli M, Gomes Ferreira LL, Chelucci RC, Michelan-Duarte S, Krogh R, Romualdo da Silva FB, Cruz FC, de Oliveira AS, Andricopulo AD, Dias LC. Espinoza-Chávez RM, et al. Among authors: de souza ml. Future Med Chem. 2024 Feb;16(3):253-269. doi: 10.4155/fmc-2023-0185. Epub 2024 Jan 9. Future Med Chem. 2024. PMID: 38193294
New drug discovery strategies for the treatment of benznidazole-resistance in Trypanosoma cruzi, the causative agent of Chagas disease.
Murta SMF, Lemos Santana PA, Jacques Dit Lapierre TJW, Penteado AB, El Hajje M, Navarro Vinha TC, Liarte DB, de Souza ML, Goulart Trossini GH, de Oliveira Rezende Júnior C, de Oliveira RB, Ferreira RS. Murta SMF, et al. Among authors: de souza ml. Expert Opin Drug Discov. 2024 May 7:1-13. doi: 10.1080/17460441.2024.2349155. Online ahead of print. Expert Opin Drug Discov. 2024. PMID: 38715393 Review.
An industrialized diet as a determinant of methylation in the 1F region of the NR3C1 gene promoter.
Vieira TDS, Freitas FV, Silva Neto LCB, Borçoi AR, Mendes SO, Olinda AS, Moreno IAA, Quaioto BR, de Souza MLM, Barbosa WM, Arpini JK, Sorroche BP, de Assis Pinheiro J, Archanjo AB, Dos Santos JG, Arantes LMRB, de Oliveira DR, da Silva AMA. Vieira TDS, et al. Among authors: de souza mlm. Front Nutr. 2024 Apr 3;11:1168715. doi: 10.3389/fnut.2024.1168715. eCollection 2024. Front Nutr. 2024. PMID: 38633601 Free PMC article.
Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials.
Gilleran JA, Ashraf K, Delvillar M, Eck T, Fondekar R, Miller EB, Hutchinson A, Dong A, Seitova A, De Souza ML, Augeri D, Halabelian L, Siekierka J, Rotella DP, Gordon J, Childers WE, Grier MC, Staker BL, Roberge JY, Bhanot P. Gilleran JA, et al. Among authors: de souza ml. J Med Chem. 2024 Mar 14;67(5):3467-3503. doi: 10.1021/acs.jmedchem.3c01795. Epub 2024 Feb 19. J Med Chem. 2024. PMID: 38372781
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Xie SC, Wang Y, Morton CJ, Metcalfe RD, Dogovski C, Pasaje CFA, Dunn E, Luth MR, Kumpornsin K, Istvan ES, Park JS, Fairhurst KJ, Ketprasit N, Yeo T, Yildirim O, Bhebhe MN, Klug DM, Rutledge PJ, Godoy LC, Dey S, De Souza ML, Siqueira-Neto JL, Du Y, Puhalovich T, Amini M, Shami G, Loesbanluechai D, Nie S, Williamson N, Jana GP, Maity BC, Thomson P, Foley T, Tan DS, Niles JC, Han BW, Goldberg DE, Burrows J, Fidock DA, Lee MCS, Winzeler EA, Griffin MDW, Todd MH, Tilley L. Xie SC, et al. Among authors: de souza ml. Nat Commun. 2024 Jan 31;15(1):937. doi: 10.1038/s41467-024-45224-z. Nat Commun. 2024. PMID: 38297033 Free PMC article.
Use of Nile tilapia (Oreocromis niloticus) processing residues in the production of pâtés with the addition of oregano (Origanum vulgare) essential oil.
Matiucci MA, Dos Santos IC, da Silva NM, Dos Santos PDS, Oliveira GG, Santos Corrêa S, Dos Santos Araujo E, Said R, Silva JF, Chambó APS, de Campos TAF, Santos OO, Alcalde CR, de Souza MLR, Feihrmann AC. Matiucci MA, et al. Among authors: de souza mlr. PLoS One. 2023 Dec 18;18(12):e0296106. doi: 10.1371/journal.pone.0296106. eCollection 2023. PLoS One. 2023. PMID: 38109370 Free PMC article.
141 results