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A comprehensive review of chalcone derivatives as antileishmanial agents.
de Mello MVP, Abrahim-Vieira BA, Domingos TFS, de Jesus JB, de Sousa ACC, Rodrigues CR, Souza AMT. de Mello MVP, et al. Among authors: de jesus jb, de sousa acc. Eur J Med Chem. 2018 Apr 25;150:920-929. doi: 10.1016/j.ejmech.2018.03.047. Epub 2018 Mar 22. Eur J Med Chem. 2018. PMID: 29602038 Review.
THC shows activity against cultured Plasmodium falciparum.
de Sousa ACC, Combrinck JM, Maepa K, Egan TJ. de Sousa ACC, et al. Bioorg Med Chem Lett. 2021 Dec 15;54:128442. doi: 10.1016/j.bmcl.2021.128442. Epub 2021 Nov 8. Bioorg Med Chem Lett. 2021. PMID: 34763083
N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.
Elworthy TR, Ford AP, Bantle GW, Morgans DJ Jr, Ozer RS, Palmer WS, Repke DB, Romero M, Sandoval L, Sjogren EB, Talamás FX, Vazquez A, Wu H, Arredondo NF, Blue DR Jr, DeSousa A, Gross LM, Kava MS, Lesnick JD, Vimont RL, Williams TJ, Zhu QM, Pfister JR, Clarke DE. Elworthy TR, et al. J Med Chem. 1997 Aug 15;40(17):2674-87. doi: 10.1021/jm970166j. J Med Chem. 1997. PMID: 9276013
Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium falciparum NSG Mouse Model.
Horatscheck A, Andrijevic A, Nchinda AT, Le Manach C, Paquet T, Khonde LP, Dam J, Pawar K, Taylor D, Lawrence N, Brunschwig C, Gibhard L, Njoroge M, Reader J, van der Watt M, Wicht K, de Sousa ACC, Okombo J, Maepa K, Egan TJ, Birkholtz LM, Basarab GS, Wittlin S, Fish PV, Street LJ, Duffy J, Chibale K. Horatscheck A, et al. Among authors: de sousa acc. J Med Chem. 2020 Nov 12;63(21):13013-13030. doi: 10.1021/acs.jmedchem.0c01411. Epub 2020 Oct 25. J Med Chem. 2020. PMID: 33103428 Free PMC article.
Correction to "Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium falciparum NSG Mouse Model".
Horatscheck A, Andrijevic A, Nchinda AT, Le Manach C, Paquet T, Khonde LP, Dam J, Pawar K, Taylor D, Lawrence N, Brunschwig C, Gibhard L, Njoroge M, Reader J, van der Watt M, Wicht K, de Sousa ACC, Okombo J, Maepa K, Egan TJ, Birkholtz LM, Basarab GS, Wittlin S, Fish PV, Street LJ, Duffy J, Chibale K. Horatscheck A, et al. Among authors: de sousa acc. J Med Chem. 2021 Feb 11;64(3):1762. doi: 10.1021/acs.jmedchem.1c00064. Epub 2021 Jan 28. J Med Chem. 2021. PMID: 33508187 No abstract available.
Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products.
Moyo P, Shamburger W, van der Watt ME, Reader J, de Sousa ACC, Egan TJ, Maharaj VJ, Bringmann G, Birkholtz LM. Moyo P, et al. Among authors: de sousa acc. Int J Parasitol Drugs Drug Resist. 2020 Aug;13:51-58. doi: 10.1016/j.ijpddr.2020.05.003. Epub 2020 May 24. Int J Parasitol Drugs Drug Resist. 2020. PMID: 32505117 Free PMC article.
18 results