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LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
Emmenegger M, De Cecco E, Hruska-Plochan M, Eninger T, Schneider MM, Barth M, Tantardini E, de Rossi P, Bacioglu M, Langston RG, Kaganovich A, Bengoa-Vergniory N, Gonzalez-Guerra A, Avar M, Heinzer D, Reimann R, Häsler LM, Herling TW, Matharu NS, Landeck N, Luk K, Melki R, Kahle PJ, Hornemann S, Knowles TPJ, Cookson MR, Polymenidou M, Jucker M, Aguzzi A. Emmenegger M, et al. Among authors: de cecco e, de rossi p. EMBO Mol Med. 2021 Sep 7;13(9):e14745. doi: 10.15252/emmm.202114745. Epub 2021 Jul 26. EMBO Mol Med. 2021. PMID: 34309222 Free PMC article.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Jambeau M, Meyer KD, Hruska-Plochan M, Tabet R, Lee CZ, Ray-Soni A, Aguilar C, Savage K, Mishra N, Cavegn N, Borter P, Lin CC, Jansen-West KR, Jiang J, Freyermuth F, Li N, De Rossi P, Pérez-Berlanga M, Jiang X, Daughrity LM, Pereira J, Narayanan S, Gu Y, Dhokai S, Dalkilic-Liddle I, Maniecka Z, Weber J, Workman M, McAlonis-Downes M, Berezovski E, Zhang YJ, Berry J, Wainger BJ, Kankel MW, Rushe M, Hock C, Nitsch RM, Cleveland DW, Petrucelli L, Gendron TF, Montrasio F, Grimm J, Polymenidou M, Lagier-Tourenne C. Jambeau M, et al. Among authors: de rossi p. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2123487119. doi: 10.1073/pnas.2123487119. Epub 2022 Dec 1. Proc Natl Acad Sci U S A. 2022. PMID: 36454749 Free PMC article.
Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.
Pérez-Berlanga M, Wiersma VI, Zbinden A, De Vos L, Wagner U, Foglieni C, Mallona I, Betz KM, Cléry A, Weber J, Guo Z, Rigort R, de Rossi P, Manglunia R, Tantardini E, Sahadevan S, Stach O, Hruska-Plochan M, Allain FH, Paganetti P, Polymenidou M. Pérez-Berlanga M, et al. Among authors: de rossi p. EMBO J. 2023 Sep 4;42(17):e111719. doi: 10.15252/embj.2022111719. Epub 2023 Jul 11. EMBO J. 2023. PMID: 37431963 Free PMC article.
FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade.
De Rossi P, Lewis AJ, Furrer J, De Vos L, Demeter T, Zbinden A, Zhong W, Wiersma VI, Scialo C, Weber J, Guo Z, Scaramuzza S, Di Fabrizio M, Böing C, Castaño-Díez D, Al-Amoudi A, Pérez-Berlanga M, Lashley T, Stahlberg H, Polymenidou M. De Rossi P, et al. Among authors: de vos l. EMBO Rep. 2021 Dec 6;22(12):e53877. doi: 10.15252/embr.202153877. Epub 2021 Nov 22. EMBO Rep. 2021. PMID: 34806807 Free PMC article.
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Scekic-Zahirovic J, Sanjuan-Ruiz I, Kan V, Megat S, De Rossi P, Dieterlé S, Cassel R, Jamet M, Kessler P, Wiesner D, Tzeplaeff L, Demais V, Sahadevan S, Hembach KM, Muller HP, Picchiarelli G, Mishra N, Antonucci S, Dirrig-Grosch S, Kassubek J, Rasche V, Ludolph A, Boutillier AL, Roselli F, Polymenidou M, Lagier-Tourenne C, Liebscher S, Dupuis L. Scekic-Zahirovic J, et al. Among authors: de rossi p. Nat Commun. 2021 May 21;12(1):3028. doi: 10.1038/s41467-021-23187-9. Nat Commun. 2021. PMID: 34021132 Free PMC article.
BIN1 localization is distinct from Tau tangles in Alzheimer's disease.
De Rossi P, Buggia-Prevot V, Andrew RJ, Krause SV, Woo E, Nelson PT, Pytel P, Thinakaran G. De Rossi P, et al. Matters (Zur). 2017 Jan;2017:10.19185/matters.201611000018. doi: 10.19185/matters.201611000018. Epub 2017 Jan 12. Matters (Zur). 2017. PMID: 29479533 Free PMC article.
VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation.
Meissirel C, Ruiz de Almodovar C, Knevels E, Coulon C, Chounlamountri N, Segura I, de Rossi P, Vinckier S, Anthonis K, Deléglise B, de Mol M, Ali C, Dassonville K, Loyens E, Honnorat J, Michotte Y, Rogemond V, Smolders I, Voets T, Vivien D, Vanden Berghe P, Van den Bosch L, Robberecht W, Chédotal A, Oliviero S, Dewerchin M, Schmucker D, Thomasset N, Salin P, Carmeliet P. Meissirel C, et al. Among authors: de mol m, de rossi p. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13782-7. doi: 10.1073/pnas.1100341108. Epub 2011 Jul 29. Proc Natl Acad Sci U S A. 2011. PMID: 21804034 Free PMC article.
78 results