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An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid.
Perrone MG, Miciaccia M, Vitale P, Ferorelli S, Araújo CDCB, de Almeida GS, Souza Domingos TF, da Silva LCRP, de Pádula M, Cabral LM, Sathler PC, Bonaccorso C, Fortuna CG, Scilimati A. Perrone MG, et al. Among authors: de padula m. Eur J Med Chem. 2021 Jan 1;209:112919. doi: 10.1016/j.ejmech.2020.112919. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33129592
Titanium dioxide-montmorillonite nanocomposite as photoprotective agent against ultraviolet B radiation-induced mutagenesis in Saccharomyces cerevisiae: a potential candidate for safer sunscreens.
Paiva JP, Santos BA, Kibwila DM, Gonçalves TC, Pinto AV, Rodrigues CR, Leitão AC, Cabral LM, De Pádula M. Paiva JP, et al. Among authors: de padula m. J Pharm Sci. 2014 Aug;103(8):2539-45. doi: 10.1002/jps.24057. Epub 2014 Jun 17. J Pharm Sci. 2014. PMID: 24942660
Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies.
Lourenço AL, Saito MS, Dorneles LE, Viana GM, Sathler PC, Aguiar LC, de Pádula M, Domingos TF, Fraga AG, Rodrigues CR, de Sousa VP, Castro HC, Cabral LM. Lourenço AL, et al. Among authors: de sousa vp, de padula m. Molecules. 2015 Apr 20;20(4):7174-200. doi: 10.3390/molecules20047174. Molecules. 2015. PMID: 25903367 Free PMC article.
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability.
Pati ML, Vitale P, Ferorelli S, Iaselli M, Miciaccia M, Boccarelli A, Di Mauro GD, Fortuna CG, Souza Domingos TF, Rodrigues Pereira da Silva LC, de Pádula M, Cabral LM, Sathler PC, Vacca A, Scilimati A, Perrone MG. Pati ML, et al. Among authors: de padula m. Eur J Med Chem. 2019 Feb 15;164:59-76. doi: 10.1016/j.ejmech.2018.12.029. Epub 2018 Dec 15. Eur J Med Chem. 2019. PMID: 30590258
Photoprotection assessment of olive (Olea europaea L.) leaves extract standardized to oleuropein: In vitro and in silico approach for improved sunscreens.
da Silva ACP, Paiva JP, Diniz RR, Dos Anjos VM, Silva ABSM, Pinto AV, Dos Santos EP, Leitão AC, Cabral LM, Rodrigues CR, de Pádula M, Santos BAMC. da Silva ACP, et al. Among authors: de padula m. J Photochem Photobiol B. 2019 Apr;193:162-171. doi: 10.1016/j.jphotobiol.2019.03.003. Epub 2019 Mar 13. J Photochem Photobiol B. 2019. PMID: 30884286
Insights and controversies on sunscreen safety.
Paiva JP, Diniz RR, Leitão AC, Cabral LM, Fortunato RS, Santos BAMC, de Pádula M. Paiva JP, et al. Among authors: de padula m. Crit Rev Toxicol. 2020 Sep;50(8):707-723. doi: 10.1080/10408444.2020.1826899. Epub 2020 Oct 16. Crit Rev Toxicol. 2020. PMID: 33064037 Review.
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