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1,2,3-triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones.
da Cruz EH, Hussene CM, Dias GG, Diogo EB, de Melo IM, Rodrigues BL, da Silva MG, Valença WO, Camara CA, de Oliveira RN, de Paiva YG, Goulart MO, Cavalcanti BC, Pessoa C, da Silva Júnior EN. da Cruz EH, et al. Among authors: de melo im, de oliveira rn, de paiva yg. Bioorg Med Chem. 2014 Mar 1;22(5):1608-19. doi: 10.1016/j.bmc.2014.01.033. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24530030 Free article.
On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
da Silva Júnior EN, de Melo IM, Diogo EB, Costa VA, de Souza Filho JD, Valença WO, Camara CA, de Oliveira RN, de Araujo AS, Emery FS, dos Santos MR, de Simone CA, Menna-Barreto RF, de Castro SL. da Silva Júnior EN, et al. Among authors: de castro sl, de melo im, de araujo as, de simone ca, de souza filho jd, de oliveira rn. Eur J Med Chem. 2012 Jun;52:304-12. doi: 10.1016/j.ejmech.2012.03.039. Epub 2012 Mar 29. Eur J Med Chem. 2012. PMID: 22483633
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
Guimarães TT, Pinto Mdo C, Lanza JS, Melo MN, do Monte-Neto RL, de Melo IM, Diogo EB, Ferreira VF, Camara CA, Valença WO, de Oliveira RN, Frézard F, da Silva EN Jr. Guimarães TT, et al. Among authors: de melo im, de oliveira rn. Eur J Med Chem. 2013 May;63:523-30. doi: 10.1016/j.ejmech.2013.02.038. Epub 2013 Mar 7. Eur J Med Chem. 2013. PMID: 23535320
Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
Diogo EB, Dias GG, Rodrigues BL, Guimarães TT, Valença WO, Camara CA, de Oliveira RN, da Silva MG, Ferreira VF, de Paiva YG, Goulart MO, Menna-Barreto RF, de Castro SL, da Silva Júnior EN. Diogo EB, et al. Among authors: de castro sl, de oliveira rn, de paiva yg. Bioorg Med Chem. 2013 Nov 1;21(21):6337-48. doi: 10.1016/j.bmc.2013.08.055. Epub 2013 Sep 6. Bioorg Med Chem. 2013. PMID: 24074878 Free article.
Distinct effects of novel naphtoquinone-based triazoles in human leukaemic cell lines.
Coulidiati TH, Dantas BB, Faheina-Martins GV, Gonçalves JC, do Nascimento WS, de Oliveira RN, Camara CA, Oliveira EJ, Lara A, Gomes ER, Araújo DA. Coulidiati TH, et al. Among authors: oliveira ej, de oliveira rn. J Pharm Pharmacol. 2015 Dec;67(12):1682-95. doi: 10.1111/jphp.12474. Epub 2015 Aug 10. J Pharm Pharmacol. 2015. PMID: 26256440
Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control.
Costa Souza RM, Montenegro Pimentel LML, Ferreira LKM, Pereira VRA, Santos ACDS, Dantas WM, Silva CJO, De Medeiros Brito RM, Andrade JL, De Andrade-Neto VF, Fujiwara RT, Bueno LL, Silva Junior VA, Pena L, Camara CA, Rathi B, De Oliveira RN. Costa Souza RM, et al. Among authors: de oliveira rn. Eur J Med Chem. 2023 Jul 5;255:115400. doi: 10.1016/j.ejmech.2023.115400. Epub 2023 Apr 18. Eur J Med Chem. 2023. PMID: 37130472
44 results