de Menezes RX - Search Results

1

Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells.

Huseinovic A, Jaspers A, van Splunter AP, Sørgård H, Wilting SM, Swarts DRA, van der Meulen IH, van Beusechem VW, de Menezes RX, Steenbergen RDM. Huseinovic A, et al. Among authors: de menezes rx. Int J Mol Sci. 2022 Apr 26;23(9):4791. doi: 10.3390/ijms23094791. Int J Mol Sci. 2022. PMID: 35563182 Free PMC article.

2

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin.

Posthumadeboer J, van Egmond PW, Helder MN, de Menezes RX, Cleton-Jansen AM, Beliën JA, Verheul HM, van Royen BJ, Kaspers GJ, van Beusechem VW. Posthumadeboer J, et al. Among authors: de menezes rx. Oncotarget. 2012 Oct;3(10):1169-81. doi: 10.18632/oncotarget.600. Oncotarget. 2012. PMID: 23045411 Free PMC article.

3

Affordable luciferase reporter assay for cell-based high-throughput screening.

Siebring-van Olst E, Vermeulen C, de Menezes RX, Howell M, Smit EF, van Beusechem VW. Siebring-van Olst E, et al. Among authors: de menezes rx. J Biomol Screen. 2013 Apr;18(4):453-61. doi: 10.1177/1087057112465184. Epub 2012 Oct 30. J Biomol Screen. 2013. PMID: 23112084

4

Analysis of small-sample clinical genomics studies using multi-parameter shrinkage: application to high-throughput RNA interference screening.

van de Wiel MA, de Menezes RX, Siebring-van Olst E, van Beusechem VW. van de Wiel MA, et al. Among authors: de menezes rx. BMC Med Genomics. 2013;6 Suppl 2(Suppl 2):S1. doi: 10.1186/1755-8794-6-S2-S1. Epub 2013 May 7. BMC Med Genomics. 2013. PMID: 23819807 Free PMC article.

5

A cell-based high-throughput screening assay for radiation susceptibility using automated cell counting.

Hodzic J, Dingjan I, Maas MJ, van der Meulen-Muileman IH, de Menezes RX, Heukelom S, Verheij M, Gerritsen WR, Geldof AA, van Triest B, van Beusechem VW. Hodzic J, et al. Among authors: de menezes rx. Radiat Oncol. 2015 Feb 27;10:55. doi: 10.1186/s13014-015-0355-2. Radiat Oncol. 2015. PMID: 25888875 Free PMC article.

6

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.

de Lange J, Faramarz A, Oostra AB, de Menezes RX, van der Meulen IH, Rooimans MA, Rockx DA, Brakenhoff RH, van Beusechem VW, King RW, de Winter JP, Wolthuis RMF. de Lange J, et al. Among authors: de menezes rx, de winter jp. Nat Commun. 2015 Oct 1;6:8399. doi: 10.1038/ncomms9399. Nat Commun. 2015. PMID: 26423134 Free PMC article.

7

The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics.

Martens-de Kemp SR, Brink A, van der Meulen IH, de Menezes RX, Te Beest DE, Leemans CR, van Beusechem VW, Braakhuis BJ, Brakenhoff RH. Martens-de Kemp SR, et al. Among authors: de menezes rx. Mol Cancer Ther. 2017 Mar;16(3):540-550. doi: 10.1158/1535-7163.MCT-16-0457. Epub 2016 Dec 15. Mol Cancer Ther. 2017. PMID: 27980104

8

A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment.

Siebring-van Olst E, Blijlevens M, de Menezes RX, van der Meulen-Muileman IH, Smit EF, van Beusechem VW. Siebring-van Olst E, et al. Among authors: de menezes rx. Mol Oncol. 2017 May;11(5):534-551. doi: 10.1002/1878-0261.12052. Epub 2017 Apr 11. Mol Oncol. 2017. PMID: 28296343 Free PMC article.

9

A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.

Amado-Azevedo J, Reinhard NR, van Bezu J, de Menezes RX, van Beusechem VW, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL. Amado-Azevedo J, et al. Among authors: de menezes rx. Sci Rep. 2017 Aug 31;7(1):10132. doi: 10.1038/s41598-017-10392-0. Sci Rep. 2017. PMID: 28860633 Free PMC article.

10

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection.

Bachas C, Hodzic J, van der Mijn JC, Stoepker C, Verheul HMW, Wolthuis RMF, Felley-Bosco E, van Wieringen WN, van Beusechem VW, Brakenhoff RH, de Menezes RX. Bachas C, et al. Among authors: de menezes rx. BMC Bioinformatics. 2018 Aug 20;19(1):301. doi: 10.1186/s12859-018-2306-z. BMC Bioinformatics. 2018. PMID: 30126372 Free PMC article.

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