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The Prodrug Approach: A Successful Tool for Improving Drug Solubility.
Jornada DH, dos Santos Fernandes GF, Chiba DE, de Melo TR, dos Santos JL, Chung MC. Jornada DH, et al. Among authors: de melo tr. Molecules. 2015 Dec 29;21(1):42. doi: 10.3390/molecules21010042. Molecules. 2015. PMID: 26729077 Free PMC article. Review.
Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions.
Yamasaki PR, do Nascimento DC, Chelucci RC, de Faria Fernandes Belone A, Rosa PS, Diório SM, de Melo TR, Barbieri KP, Placeres MC, Carlos IZ, Chung MC, dos Santos JL. Yamasaki PR, et al. Among authors: de melo tr. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3084-7. doi: 10.1016/j.bmcl.2014.05.017. Epub 2014 May 16. Bioorg Med Chem Lett. 2014. PMID: 24907144
A thalidomide-hydroxyurea hybrid increases HbF production in sickle cell mice and reduces the release of proinflammatory cytokines in cultured monocytes.
Lanaro C, Franco-Penteado CF, Silva FH, Fertrin KY, Dos Santos JL, Wade M, Yerigenahally S, de Melo TR, Chin CM, Kutlar A, Meiler SE, Costa FF. Lanaro C, et al. Among authors: de melo tr. Exp Hematol. 2018 Feb;58:35-38. doi: 10.1016/j.exphem.2017.10.003. Epub 2017 Nov 3. Exp Hematol. 2018. PMID: 29108926 Free article.
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