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Page 1
Collaboration across boundaries in the Amazon.
Prist PR, Levin N, Metzger JP, de Mello K, de Paula Costa MD, Castagnino R, Cortes-Ramirez J, Lin DL, Butt N, Lloyd TJ, López-Cubillos S, Mayfield HJ, Negret PJ, Oliveira-Bevan I, Reside AE, Rhodes JR, Simmons BA, Suárez-Castro AF, Kark S. Prist PR, et al. Among authors: de mello k. Science. 2019 Nov 8;366(6466):699-700. doi: 10.1126/science.aaz7489. Science. 2019. PMID: 31699929 No abstract available.
Osteopontin-c splicing isoform contributes to ovarian cancer progression.
Tilli TM, Franco VF, Robbs BK, Wanderley JL, da Silva FR, de Mello KD, Viola JP, Weber GF, Gimba ER. Tilli TM, et al. Among authors: de mello kd. Mol Cancer Res. 2011 Mar;9(3):280-93. doi: 10.1158/1541-7786.MCR-10-0463. Epub 2011 Jan 24. Mol Cancer Res. 2011. PMID: 21263033
5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile.
Sakya SM, Hou X, Minich ML, Rast B, Shavnya A, DeMello KM, Cheng H, Li J, Jaynes BH, Mann DW, Petras CF, Seibel SB, Haven ML. Sakya SM, et al. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1067-72. doi: 10.1016/j.bmcl.2006.11.026. Epub 2006 Nov 15. Bioorg Med Chem Lett. 2007. PMID: 17126015
5-heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure-activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog.
Sakya SM, DeMello KM, Minich ML, Rast B, Shavnya A, Rafka RJ, Koss DA, Cheng H, Li J, Jaynes BH, Ziegler CB, Mann DW, Petras CF, Seibel SB, Silvia AM, George DM, Lund LA, St Denis S, Hickman A, Haven ML, Lynch MP. Sakya SM, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):288-92. doi: 10.1016/j.bmcl.2005.10.006. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275075
Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine.
Li J, DeMello KM, Cheng H, Sakya SM, Bronk BS, Rafka RJ, Jaynes BH, Ziegler CB, Kilroy C, Mann DW, Nimz EL, Lynch MP, Haven ML, Kolosko NL, Minich ML, Li C, Dutra JK, Rast B, Crosson RM, Morton BJ, Kirk GW, Callaghan KM, Koss DA, Shavnya A, Lund LA, Seibel SB, Petras CF, Silvia A. Li J, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):95-8. doi: 10.1016/j.bmcl.2003.10.004. Bioorg Med Chem Lett. 2004. PMID: 14684306