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Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor.
Gomes PS, Carneiro MPD, Machado PA, de Andrade-Neto VV, da Fonseca-Martins AM, Goundry A, Pereira da Silva JVM, Gomes DCO, Lima APCA, Ennes-Vidal V, Sodero ACR, De-Simone SG, de Matos Guedes HL. Gomes PS, et al. Among authors: de matos guedes hl. Curr Issues Mol Biol. 2022 May 9;44(5):2089-2106. doi: 10.3390/cimb44050141. Curr Issues Mol Biol. 2022. PMID: 35678670 Free PMC article.
Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection.
de Matos Guedes HL, da Silva Costa BL, Chaves SP, de Oliveira Gomes DC, Nosanchuk JD, De Simone SG, Rossi-Bergmann B. de Matos Guedes HL, et al. Among authors: de simone sg, de oliveira gomes dc. Parasit Vectors. 2014 Sep 19;7:448. doi: 10.1186/1756-3305-7-448. Parasit Vectors. 2014. PMID: 25239157 Free PMC article.
Efficacy of intranasal LaAg vaccine against Leishmania amazonensis infection in partially resistant C57Bl/6 mice.
Pratti JE, Ramos TD, Pereira JC, da Fonseca-Martins AM, Maciel-Oliveira D, Oliveira-Silva G, de Mello MF, Chaves SP, Gomes DC, Diaz BL, Rossi-Bergmann B, de Matos Guedes HL. Pratti JE, et al. Among authors: de mello mf, de matos guedes hl. Parasit Vectors. 2016 Oct 6;9(1):534. doi: 10.1186/s13071-016-1822-9. Parasit Vectors. 2016. PMID: 27716449 Free PMC article.
Oligopeptidase B and B2: comparative modelling and virtual screening as searching tools for new antileishmanial compounds.
Sodero AC, Dos Santos AC, Mello JF, DE Jesus JB, DE Souza AM, Rodrigues MI, DE Simone SG, Rodrigues CR, DE Matos Guedes HL. Sodero AC, et al. Among authors: de simone sg, de jesus jb, de souza am, de matos guedes hl. Parasitology. 2017 Apr;144(4):536-545. doi: 10.1017/S0031182016002237. Epub 2016 Dec 29. Parasitology. 2017. PMID: 28031079
Effects of Bone Marrow Mesenchymal Stromal Cell Therapy in Experimental Cutaneous Leishmaniasis in BALB/c Mice Induced by Leishmania amazonensis.
Pereira JC, Ramos TD, Silva JD, de Mello MF, Pratti JES, da Fonseca-Martins AM, Firmino-Cruz L, Kitoko JZ, Chaves SP, Gomes DCO, Diaz BL, Rocco PRM, de Matos Guedes HL. Pereira JC, et al. Among authors: de mello mf, de matos guedes hl. Front Immunol. 2017 Aug 10;8:893. doi: 10.3389/fimmu.2017.00893. eCollection 2017. Front Immunol. 2017. PMID: 28848541 Free PMC article.
Immunomodulating role of IL-10-producing B cells in Leishmania amazonensis infection.
Firmino-Cruz L, Ramos TD, da Fonseca-Martins AM, Maciel-Oliveira D, Oliveira-Silva G, Pratti JES, Cavazzoni C, Chaves SP, Oliveira Gomes DC, Morrot A, Freire-de-Lima L, Vale AM, Freire-de-Lima CG, Decote-Ricardo D, de Matos Guedes HL. Firmino-Cruz L, et al. Among authors: de matos guedes hl. Cell Immunol. 2018 Dec;334:20-30. doi: 10.1016/j.cellimm.2018.08.014. Epub 2018 Aug 22. Cell Immunol. 2018. PMID: 30170688
Leishmanicidal therapy targeted to parasite proteases.
Machado PA, Carneiro MPD, Sousa-Batista AJ, Lopes FJP, Lima APCA, Chaves SP, Sodero ACR, de Matos Guedes HL. Machado PA, et al. Among authors: de matos guedes hl. Life Sci. 2019 Feb 15;219:163-181. doi: 10.1016/j.lfs.2019.01.015. Epub 2019 Jan 11. Life Sci. 2019. PMID: 30641084 Review.
The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy.
Pratti JES, da Fonseca Martins AM, da Silva JP, Ramos TD, Pereira JC, Firmino-Cruz L, Oliveira-Maciel D, Vieira TSS, Lacerda LL, Vale AM, Freire-de-Lima CG, Gomes DCO, Saraiva EM, Rossi-Bergmann B, de Matos Guedes HL. Pratti JES, et al. Among authors: de matos guedes hl. PLoS Negl Trop Dis. 2019 Feb 25;13(2):e0007146. doi: 10.1371/journal.pntd.0007146. eCollection 2019 Feb. PLoS Negl Trop Dis. 2019. PMID: 30802247 Free PMC article.
51 results