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In vitro and in silico studies for barbinervic acid, a triterpene isolated from Eugenia punicifolia that inhibits vasopressor tone.
Teixeira RGS, de Pascual R, Lima-Araújo KG, de Brito MA, de Los Rios C, do Carmo AF, Gandía L, Silva CLM, Machado TB, Santos WC. Teixeira RGS, et al. Among authors: de brito ma, de pascual r, de los rios c. Nat Prod Res. 2021 Nov;35(22):4870-4875. doi: 10.1080/14786419.2020.1739675. Epub 2020 Mar 16. Nat Prod Res. 2021. PMID: 32174171
Gramine Derivatives Targeting Ca(2+) Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases.
Lajarín-Cuesta R, Nanclares C, Arranz-Tagarro JA, González-Lafuente L, Arribas RL, Araujo de Brito M, Gandía L, de Los Ríos C. Lajarín-Cuesta R, et al. Among authors: de los rios c. J Med Chem. 2016 Jul 14;59(13):6265-80. doi: 10.1021/acs.jmedchem.6b00478. Epub 2016 Jun 24. J Med Chem. 2016. PMID: 27280380 Free article.
The quantal catecholamine release from mouse chromaffin cells challenged with repeated ACh pulses is regulated by the mitochondrial Na+ /Ca2+ exchanger.
López-Gil A, Nanclares C, Méndez-López I, Martínez-Ramírez C, de Los Rios C, Padín-Nogueira JF, Montero M, Gandía L, García AG. López-Gil A, et al. Among authors: de los rios c. J Physiol. 2017 Mar 15;595(6):2129-2146. doi: 10.1113/JP273339. Epub 2017 Feb 7. J Physiol. 2017. PMID: 27982456 Free PMC article.
Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles.
Samadi A, Valderas C, de los Ríos C, Bastida A, Chioua M, González-Lafuente L, Colmena I, Gandía L, Romero A, Del Barrio L, Martín-de-Saavedra MD, López MG, Villarroya M, Marco-Contelles J. Samadi A, et al. Among authors: de los rios c. Bioorg Med Chem. 2011 Jan 1;19(1):122-33. doi: 10.1016/j.bmc.2010.11.040. Epub 2010 Nov 26. Bioorg Med Chem. 2011. PMID: 21163662
Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists.
Tomassoli I, Ismaili L, Pudlo M, de Los Ríos C, Soriano E, Colmena I, Gandía L, Rivas L, Samadi A, Marco-Contelles J, Refouvelet B. Tomassoli I, et al. Among authors: de los rios c. Eur J Med Chem. 2011 Jan;46(1):1-10. doi: 10.1016/j.ejmech.2010.08.054. Epub 2010 Dec 15. Eur J Med Chem. 2011. PMID: 21111515
84 results